Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: - | CAS number: -
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
For the substance registered no specific metabolism or kinetic study is available. All information for a toxicokinetic assessment is taken from study results performed with the test substance.
Key value for chemical safety assessment
- Bioaccumulation potential:
- low bioaccumulation potential
- Absorption rate - oral (%):
- 100
- Absorption rate - dermal (%):
- 10
- Absorption rate - inhalation (%):
- 100
Additional information
Results from oral toxicity studies in rats up to 28 days indicated that there is systemic availability of the substance or metabolites at a high oral dosage. Direct evidence in the form of plasma data is not available.
No evidence of dermal bioavailability is given, although adsorption of the dyestuff was noted in the acute dermal toxicity study (i.e. yellow discoloration at the application area). The level of inhalation exposure is negligible due to the low vapour pressure. Inhalation of dust of the substance is not likely as the substance is manufactured as aqueous solution and the solid is only generated for registration purposes.
Observation of dark yellow discoloration of the urine after repeated oral administration indirectly shows a certain distribution of the substance in the body. The estimated low log POW indicates a low potential for accumulation in fatty tissues.
Excretion of the substance in the form of discoloration is observed in urine and feces; direct evidence in the form of analytical data is not available.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
