Registration Dossier
Registration Dossier
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EC number: 605-788-5 | CAS number: 17696-11-6
Endpoint summary
Administrative data
Description of key information
An in vivo Acute dermal irritation/corrosion study in rabbit (OECD Guideline 404) is available on the similar substance octanoic acid CAS no. 124-07-2.
An in vivo Acute Eye irritation/corrosion study in rabbit (OECD Guideline 405) is available on the similar substance octanoic acid CAS no. 124-07-2.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (corrosive)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Additional information
Justification for classification or non-classification
In the Acute dermal irritation/corrosion study with octanoic acid, full thickness necrosis was observed at reading time point 48 h in all animals.
In the Acute Eye irritation/corrosion study with octanoic acid, the test item produced irritant ocular effects, conjunctival rednesses, chemosis, discharge and corneal lesions after application.
The test material octanoic acid is considered to be corrosive. It is reasonable that the substance 8-bromooctanoic acid could also be corrosive.
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