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EC number: 406-250-0 | CAS number: 72619-32-0 HALOXYFOP R-(+)-ME HERBICIDAL CHEMICAL
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- In the absence of data on the microbial toxicity the test concentration used in the ready biodegradation study can be used as the NOEC to fill the ‘Toxicity to microbes’ endpoint requirements (ECHA, 2017, R7b). Please refer to section 5.2.1 for the full study summary.
- Reason / purpose for cross-reference:
- reference to other study
- Qualifier:
- according to guideline
- Guideline:
- other: OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: EU Method C.6 (Degradation: Chemical Oxygen Demand)
- Deviations:
- no
- GLP compliance:
- yes
- Specific details on test material used for the study:
- XRD 535 Me
Lot # : GHD-2413-21
Purity: 93.9% - Test organisms (species):
- activated sludge
- Details on inoculum:
- - Source of inoculum/activated sludge: The aeration stage of the HRC Limited sewage treatment plant treating predominantly domestic sewage
- Preparation of inoculum for exposure: The sample was allowed to settle and the supernatant filtered through Whatman GFA filter paper (first 250 mL discarded) - Limit test:
- no
- Total exposure duration:
- 28 d
- Test temperature:
- 20 ± 1°C
- Nominal and measured concentrations:
- 3 mg/L
- Details on test conditions:
- TEST CONDITIONS
- Composition of medium: Standard nutrient medium (solution 1: KH2PO4, K2HPO4, Na2H PO4.2H2O, NH4Cl; solution 2: MgSO4.7H2O; solution 3: CaCl2; Solution 4: FeCl3.6H2O)
- Test temperature: 20 ± 1°C
- Continuous darkness: Yes
TEST SYSTEM
- Culturing apparatus: 280 mL BOD bottles (darkened glass) with ground glass stoppers
- Number of culture flasks/concentration: 2
- Test performed in closed vessels due to significant volatility of test substance: Closed vessels
SAMPLING
- Sampling frequency: 0, 5, 15 or 28 days
CONTROL AND BLANK SYSTEM
- Inoculum blank: Inoculated dilution water; inoculated dilution water and filter paper
- Abiotic sterile control: Non-inoculated dilution water - Duration:
- 28 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 3 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: biodegradability
- Conclusions:
- The test substance attained between 8-11% degradation after 28 days and therefore cannot be termed as readily biodegradable.
- Executive summary:
The ready biodegradability of the test substance was assessed using a closed bottle procedure according to EEC directive C6 and OECD guideline 301D.
The test substance attained between 8-11% degradation after 28 days and therefore cannot be termed as readily biodegradable.
The standard substances, sodium benzoate and aniline, attained 81-83% and 59% degradation respectively within 28 days.
Oxygen depletions in the inoculated and non-inoculated control series were within the prescribed limits.
Reference
Description of key information
28-day NOEC (activated sludge) = 3 mg/L; OECD 301 D, EU Method C.6; Reliability = 1
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 3 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.