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EC number: 424-510-1 | CAS number: 220150-59-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
ErC50 (72 hours, Scenedesmus subspicatus) = 14.6 mg/l (mean measured)
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 14.6 mg/L
Additional information
The toxicity of the test item to algae was evaluated in an experimental study on Scenedesmus subspicatus according to the OECD Guideline 201 (1984) and the EU Method C.3 (1992). The test method was modified to quantify the algicidal effect of the test item, but also the growth inhibition effect due to the reduced light intensities in the coloured test media. 10,000 Scenedesmus subspicatus per ml of test media were cultured and inoculated, then allowed to grow in 50 ml Erlenmeyer flasks containing 15 ml algal suspension, in triplicate, at test item concentrations of 1.9, 6.1, 19.5, 62.5 and 200 mg/l for 72 hours in a temperature-controlled, continuously lit water bath. A control containing no test item (six replicates) was also tested in parallel. Cell densities were recorded at 24, 48 and 72 hours.
The analytically determined test substance concentrations in the analysed test media at the start of the test varied in the range from 88 % to 96 % of the nominal values. During the test period of 72 hours a decrease of test substance concentration in the test media was determined. The mean measured test concentrations (calculated as the average over all measurements per test concentration) varied in the range of 77 % to 91 % of the nominal values. Therefore, the reported biological results are related to the mean measured test substance concentrations.
Test media of concentrations of 6.1 mg/l test item and over were slightly to strongly discoloured by the test item. Toxicity was due in part to the indirect effect of inhibited light absorption due to discolouration caused by the test item, however at higher test item concentrations a real toxic effect of the test item on the growth of Scenedesmus subspicatus cannot be excluded. The 72-hour EC50 was determined to be 14.6 mg/l based on the growth rate, and 4.8 mg/l based on biomass.
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