N,N-dimethyl-N-tetradecyltetradecan-1-aminium chloride

Flammability

Link to relevant study record(s)

Reference

Endpoint:

flammable solids

Type of information:

read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

key study

Justification for type of information:

REPORTING FORMAT FOR THE ANALOGUE APPROACH

1. HYPOTHESIS FOR THE ANALOGUE APPROACH
This read-across is based on the hypothesis that source and target substances have similar toxicological properties because
• they are manufactured from similar or identical precursors under similar conditions
• they share structural similarities with common functional groups: quaternary ammonium and saturated or unsaturated alkyl chains with comparable length (corresponding to scenario 2 of the read-across assessment framework)

The read-across hypothesis is based on structural similarity of target and source substances. Based on available experimental data, including key physicochemical properties and data from acute toxicity, irritation, sensitization (human) and genotoxicity studies, the read-across strategy is supported by a quite similar toxicological profile of all substances.

Therefore, read-across from the existing ecotoxicity, environmental fate and toxicity studies conducted with the source substances is considered as an appropriate adaptation to the standard information requirements of the REACH Regulation for the target substance, in accordance with the provisions of Annex XI, 1.5 of the REACH Regulation.

A justification for read-across is attached to IUCLID section 13.

2. SOURCE AND TARGET CHEMICAL(S) (INCLUDING INFORMATION ON PURITY AND IMPURITIES)
See justification for read-across attached to IUCLID section 13.

3. ANALOGUE APPROACH JUSTIFICATION
See justification for read-across attached to IUCLID section 13.

4. DATA MATRIX
See justification for read-across attached to IUCLID section 13.

Reason / purpose for cross-reference:

read-across source

Reason / purpose for cross-reference:

read-across: supporting information

GLP compliance:

no

Test procedure:

burning rate test: preliminary screening test

Moisture (wt %):

0.1

Remarks on result:

substance does not ignite and propagate combustion either by burning with flame or smouldering along 200 mm of the powder train within the 2 minutes test period

Remarks:

In the preliminary test using a gas flame the sample showed only melting. Therefore no propagation of combustion was given.

Interpretation of results:

GHS criteria not met

Description of key information

non-flammable (UN-N.1, preliminary test) (read-across from Di-C14-18 alkyldimethyl ammonium methosulfate)

Key value for chemical safety assessment

Flammability:

not classified

Additional information

No experimental data are available for the target substance Di-C12-18 alkyl-dimethyl ammonium chloride. However, a study on flammability was conducted with the structurally related substance

Di-C14-18 alkyldimethyl ammonium methosulfate. A justification for read-across is attached to IUCLID section 13.

The flammability of Di-C14-18 alkyldimethyl ammonium methosulfate was determined in a UN-N.1 preliminary test. The test item only melted, when a gas flame the was applied.

Therefore, no propagation of combustion was given. The conduct of the definitive test was not required. The test item does not fulfil the criteria for the transport class 4.1 “readily combustible solids”.