Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 257-407-3 | CAS number: 51772-85-1
Endpoint summary
Administrative data
Description of key information
Additional information
There are no reliable aquatic toxicity data available for 3-[tris(acetoxy)silyl]propyl methacrylate (CAS 51772-85-1), therefore good quality data for the structurally-related substance, 3-trimethoxysilylpropyl methacrylate (CAS 2530-85-0), have been read across. Refer to IUCLID Section 6 endpoint summary for further discussion of the justification for read across.
Reliable acute toxicity tests results are available for freshwater fish (Brachydanio rerio), invertebrates (Daphnia magna) and algae (Scenedesmus subspicatus) for 3-trimethoxysilylpropyl methacrylate. The relevant short-term values are:
Fish: LC50 (96 h): >100 mg/l and >1042 mg/l; NOEC: ≥100 mg/l and ≥1042 mg/l
Daphnia: EC50 (48 h): >100 mg/ l and >876 mg/l; NOEC: ≥100 mg/l and ≥876 mg/l
Algae: EC50 (72 h): >100 mg/l and >536 mg/l; NOEC: ≥100 mg/l and 322 mg/l
An activated sludge respiration inhibition 3 hour EC50 value of >1000 mg/l and NOEC value of ≥1000 mg/l (nominal) were determined in a reliable study.
The rapid hydrolysis of 3-trimethoxysilylpropyl methacrylate (half-life 1.7 h at pH 7 and 20-25 °C) means it is likely that the test organisms in each test were exposed primarily to the hydrolysis products, 3-(trihydroxysilyl)propyl methacrylate and methanol. The activated sludge respiration inhibition has a 3 hour duration, and so test organisms may have had more exposure to the parent substance. As the parent substance has a higher log Kowvalue, read-across of this result is considered to reflect a worst case.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
