Registration Dossier
Registration Dossier
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EC number: 682-678-3 | CAS number: 182121-12-6
Genetic toxicity: in vivo
Administrative data
- Endpoint:
- in vivo mammalian somatic cell study: cytogenicity / bone marrow chromosome aberration
- Type of information:
- other: review article
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- abstract
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- EFSA 16the list of FCM substances
- Author:
- EFSA
- Year:
- 2 007
- Bibliographic source:
- EFSA/AFC/FCM/1033-Rev.IIA (39815 of May 2007)
Materials and methods
- Principles of method if other than guideline:
- rat bone marrow chromosome analysis
Test material
- Reference substance name:
- 9,9-Bis(methoxymethyl)-9H-fluorene
- EC Number:
- 682-678-3
- Cas Number:
- 182121-12-6
- Molecular formula:
- C17H18O2
- IUPAC Name:
- 9,9-Bis(methoxymethyl)-9H-fluorene
- Test material form:
- solid: particulate/powder
Constituent 1
- Specific details on test material used for the study:
- 9,9-Bis(methoxymethyl)fluorene
Test animals
- Species:
- rat
Results and discussion
Test results
- Key result
- Genotoxicity:
- negative
- Additional information on results:
- data from a review article
Applicant's summary and conclusion
- Conclusions:
- In this reviwe article the rat bone marrow chromosome analysis was considered to be negative.
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