Registration Dossier
Registration Dossier
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EC number: 235-406-9 | CAS number: 12220-06-3
Endpoint summary
Administrative data
Description of key information
Not harmful/toxic for aquatic life.
Additional information
Adequate chronic toxicity data are not available for Acid Orange 067, therefore the aquatic toxicity assessment and classification are based mainly on the short-term toxicity data available.
Acid Orange 067 is soluble in water (i.e. 0.33 ± 0.05 g/l at 20 °C pH ca 9); however, in the daphnia/lemma media the solubility resulted to be significantly decreased. The observed behaviour is not unusual for acid and basic dyes; based on experience in application, it is known that dyeing with acid dyes may be problematic in case of medium with an high content of ions like calcium and magnesium. Unfortunately, the systems to increase the water solubility cannot be applied to the biological daphnia/lemna testing media (e.g. usage of chelating agents for calcium and magnesium ions) because they can reduce also the availability of nutrients.
Acid Orange 067 is not rapidly degradable, however it has a log Kow lower than 4, indicating a low potential for bioaccumulation.
According to the CLP Regulation (EC) No 1272/2008, acute aquatic toxicity is normally determined using a fish 96-hour LC50, a crustacean species 48-hour EC50 and/or an algal species 72- or 96-hour EC50; nevertheless it is also specified in the Regulation that data on other species (e.g. Lemna spp.) shall also be considered if the test methodology is suitable.
The mentioned species cover a range of trophic levels and taxa and are considered as surrogate for all aquatic organisms. Data are available for fish (guppy), Daphnia magna and Lemna gibba.
No L(E)C50 value was recorded at concentration equal/lower than 1 mg/l, thus the classification criteria for acute (short-term) aquatic hazard (category 1) of the CLP Regulation (EC) No 1272/2008 are not met.
In addition, no acute toxicity (i.e. L(E)C50) was recorded in none of the experiments conducted, up to the higher concentration reached in the tests; thus the classification criteria for long-term aquatic hazard (categories 2/3/4) of the CLP Regulation (EC) No 1272/2008 are not met.
In conclusion, the outcomes of the tests performed on the three trophic levels suggest that Acid Orange 067 is not harmful/toxic for aquatic life.
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