Registration Dossier
Registration Dossier
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EC number: 205-206-6 | CAS number: 135-62-6
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2011
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 011
- Report date:
- 2011
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Type of method:
- shake-flask method to: flask method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- 3-hydroxy-2'-methoxy-2-naphthanilide
- EC Number:
- 205-206-6
- EC Name:
- 3-hydroxy-2'-methoxy-2-naphthanilide
- Cas Number:
- 135-62-6
- Molecular formula:
- C18H14NNaO3
- IUPAC Name:
- 3-hydroxy-2'-methoxy-2-naphthanilide
Constituent 1
Study design
- Analytical method:
- photometric method
Results and discussion
Partition coefficient
- Type:
- log Pow
- Partition coefficient:
- 2.9
- Temp.:
- 23 °C
- pH:
- ca. 7
Any other information on results incl. tables
Results in detail:
| determ. no. | stock solution [ml] | water [ml] | test substance conc. in n-octanol phase [mg/l] | test substance conc. in water phase [mg/l] | log Pow |
| A1 | 5 | 10 | 1208,9 | 0,7 | 3,2 |
| A2 | 5 | 10 | 1203,1 | 0,8 | 3,2 |
| B1 | 10 | 10 | 1173,3 | 1,5 | 2,9 |
| B2 | 10 | 10 | 1192,1 | 1,4 | 2,9 |
| C1 | 20 | 10 | 1190,1 | 2,4 | 2,7 |
| C2 | 20 | 10 | 1186,2 | 2,8 | 2,6 |
| mean | --- | --- | --- | --- | 2,9 |
Stock solution: 1230 mg/l
Applicant's summary and conclusion
- Conclusions:
- The partition coefficient n-octanol/water for the test item was determined according OECD 107 as 2.9 at 23°C.
- Executive summary:
The partition coefficient n-octanol/water (logPow) for the test item was determined according OECD 107 as 2.9 at 23°C.
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