Registration Dossier
Registration Dossier
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EC number: 250-807-9 | CAS number: 31795-24-1
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
Testing for long-term toxicity to fish is not considered necessary because:
According to Regulation (EC) No. 1907/2006, Annex IX, Column 2, long term testing shall be proposed if the chemical safety assessment according to Annex I indicates the need to further investigate the effects on aquatic organisms. Potassium methylsilanetriolate (CAS No. 31795-24-1) rapidly dissociates on contact with water, and the ionisation state will reflect the prevailing pH conditions. In the neutral pH range the silanetriolate will be present as methylsilanetriol. Methylsilanetriol, the substance upon which the chemical safety assessment is based, does not have the potential to bioaccumulate. It has very low log Kow, therefore its bioavailability is expected to be limited and, as the substance acts via a non-polar narcotic mechanism of toxicity, toxicity is not expected. Short-term toxicity of the test substance to fish is low within the normal pH range, with no effects seen at the highest concentrations tested. Results from tests carried out with invertebrates and algae, including a long-term Daphnia study, also showed no effects at the highest concentrations tested. Thus, toxicity of methylsilanetriol to fish species is not expected. Considering this information and for animal welfare reasons, long-term testing with fish is not deemed necessary.
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