6-amino-4-hydroxynaphthalene-2-sulphonic acid

Boiling point

Administrative data

Endpoint:

boiling point

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance is a solid which melts above 300°C

Cross-reference

Reason / purpose for cross-reference:

data waiving: supporting information

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Version / remarks:

Council Regulation (EC) No 440/2008 A.1 (ASTM E 537)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

other: thermal analysis and capillary method

Key result

Melting / freezing pt.:

> 355 °C

Decomposition:

no

Sublimation:

no

Remarks on result:

other: no melting has been observed up to 355 °C

Conclusions:

The GLP study was performed according to EU method A.1 without deviations and therefore reliability of Klimisch 1 has been assigned. From 310 °C there was a slowly changing of the colour to grey/brown but no melting up to
355 °C.

Executive summary:

The melting point of the test substance was determined in a GLP test according to EU method A.1 using the DSC method first. As the effects were not reproducable the substance was heated using the capillary method in a melting device with liquid bath in order to observe the melting behaviour. The substance was heated up to 270 °C and then heated with a rate of 2 K/min. Until a temperature of 310 °C there were no optical changes. From 310 °C there were a slowly changing of the colour to grey/brown but no melting up to 355 °C. At the end of the measurement the substance was dark and a little sintered.