Registration Dossier
Registration Dossier
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EC number: 606-198-0 | CAS number: 19011-80-4
Melting point / freezing point
Administrative data
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- publication
- Title:
- Quinazolines and 1,4-Benzodiazepines. XL. 1 The Synthesis of l\1etabolites of 7-Chloro-l-(2-diethylaminoethyl)-5-(2-fluorophenyl) l,3-dihydro-2H-l,4-benzodiazepin-2-one
- Author:
- Earley et al.
- Year:
- 1 968
- Bibliographic source:
- Journal of medicinal chemistry; vol.11; nb. 4; p. 774 - 777;
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- no data on method available
- GLP compliance:
- not specified
- Type of method:
- other: no data
Test material
- Reference substance name:
- 7-chloro-5-(2-fluorophenyl)-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl acetate
- EC Number:
- 606-198-0
- Cas Number:
- 19011-80-4
- Molecular formula:
- C17H12ClFN2O3
- IUPAC Name:
- 7-chloro-5-(2-fluorophenyl)-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl acetate
- Test material form:
- solid
Constituent 1
Results and discussion
Melting / freezing point
- Key result
- Melting / freezing pt.:
- >= 239 - <= 247 °C
- Remarks on result:
- other: Solvent methanol
Applicant's summary and conclusion
- Conclusions:
- The melting point of 7-Chlor-5-(o-fluorphenyl)-1,3-dihydro-3-acetoxy-2H-1,4-benzodiazepin-2-on is reported to be 239 - 247°C.
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