Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Additional toxicological data

Currently viewing:

Administrative data

Endpoint:
additional toxicological information
Type of information:
read-across based on grouping of substances (category approach)
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: only short abstract available
Justification for type of information:
Read across is based on the category approach. Please refer to attached category document.

Data source

Reference
Reference Type:
review article or handbook
Title:
An assessment of the developmental toxicity of TEG and TEGDE in Drosophila melanogaster.
Author:
Lynch, D.W.
Year:
1996
Bibliographic source:
SOT 1996 Annual Meeting, Article 994

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
2,2'-(ethylenedioxy)diethanol
EC Number:
203-953-2
EC Name:
2,2'-(ethylenedioxy)diethanol
Cas Number:
112-27-6
Molecular formula:
C6H14O4
IUPAC Name:
2,2'-[ethane-1,2-diylbis(oxy)]diethanol
Details on test material:
Triethylene glycol
CAS: 112-27-6
no further details

Results and discussion

Any other information on results incl. tables

The incidence of bent bristles was statistically increased compared to concurrent controls at the 2 highest TEG concentrations (38/181 at 1.33 mM; 29/99 at 1.64 mM).

Applicant's summary and conclusion