Registration Dossier
Registration Dossier
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EC number: 217-162-5 | CAS number: 1759-53-1
PBT assessment
Administrative data
PBT assessment: overall result
- Name:
- Cyclopropane carboxylic acid
- Type of composition:
- legal entity composition of the substance
- State / form:
- liquid
- Reference substance:
- Cyclopropane carboxylic acid
- PBT status:
- the substance is not PBT / vPvB
- Justification:
Cyclopropane carboxylic acid (CPCA) - CAS No. 1759 – 53 -1
The environmental assessment using EPIWIN of shows that the substance Cyclopropane carboxylic acid - CAS No. 1759 – 53 -1 does not meet the criteria for classification as PTB or vPTB.
It is expected that the substance being a carboxylic acid will readily dissociate in water. The substance has a very low Log Kow measured at: Log Kow 1.68. This low Log Kow is an indication that the substance is likely to remain in water indicating not be B or vB. In addition the bioaccumulation factor (predicted from valid EPI suit) is extremely low at 3.162 L/kg. This is well below the > 2000 L/kg threshold which again indicated not B or vB.
With respect to the persistency the predicted (EPI suit) Biowin 3 degradation rate is 3.3 and is a strong indication that the substance will biodegrades fast (days – weeks). The Biowin 2 probability is above 0.5 (estimated probability 0.99) again giving a further indication that the substance will biodegrade fast. The third key prediction from the EPI suit results, Biowin 5, indicates a probability above 0.5 (estimated probability 0.689) giving an indication that the substance will again biodegrade readily. In summary the Biowin 3 (ultimate survey model) results in ‘days to weeks’ and the Biowin 5 (MITI linear model) has a probability above 0.5 and so the prediction is yes, the substance will readily biodegrade . The overall assessment of the EPI suit predictions is that the substance is not P or vP.
Cyclopropane carboxylic acid is not classified as carcinogenic (cat 1A or 1B), cell mutagenic (category 1A or 1B) or toxic for reproduction (category 1A, 1B or 2) in accordance with EC No. 1272/2008. The substance has been listed in Annex III but this is no firm indication that the substance should be classified as CMR. Based on all of the above the substance is not PTB.
Further PTB assessment is not thought necessary.
The substance is not classified as PBT therefore there route of exposure is not relevant
- Likely routes of exposure:
No routes of exposure as it is not PBT
Reference
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