Registration Dossier
Registration Dossier
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EC number: 211-780-9 | CAS number: 695-34-1
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Data obtained from an authoritative secondary source.
Data source
Reference
- Reference Type:
- secondary source
- Title:
- Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 53, Pg. 227S, 1957. (2-Amino-4-methylpyridine)
- Year:
- 1 957
- Bibliographic source:
- http://chem.sis.nlm.nih.gov/chemidplus/rn/695-34-1
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Version / remarks:
- Data cited in ChemIDplus database with reference.
- Principles of method if other than guideline:
- Data cited in ChemIDplus database. Only result is provided on the database.
- GLP compliance:
- not specified
- Remarks:
- No other information from the data source.
Test material
- Reference substance name:
- 4-methyl-2-pyridylamine
- EC Number:
- 211-780-9
- EC Name:
- 4-methyl-2-pyridylamine
- Cas Number:
- 695-34-1
- Molecular formula:
- C6H8N2
- IUPAC Name:
- 4-methylpyridin-2-amine
- Reference substance name:
- 2-Amino-4-methylpyridine
- IUPAC Name:
- 2-Amino-4-methylpyridine
- Test material form:
- solid: particulate/powder
Constituent 1
Constituent 2
- Specific details on test material used for the study:
- No specific details on test material used for the study was provided.
Test animals
- Species:
- mouse
- Strain:
- not specified
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- No other information from the data source.
Administration / exposure
- Route of administration:
- subcutaneous
- Vehicle:
- not specified
- Details on exposure:
- No other information from the data source.
- Doses:
- No data
- No. of animals per sex per dose:
- No data
- Control animals:
- not specified
- Details on study design:
- No other information from the data source.
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- ca. 64 mg/kg bw
- Based on:
- not specified
- Remarks on result:
- other: Data obtained from an authoritative secondary source.
- Mortality:
- No data
- Clinical signs:
- No data
- Body weight:
- No data
- Gross pathology:
- No data
- Other findings:
- No data
Applicant's summary and conclusion
- Conclusions:
- The LD50 of mice is found to be 64 mg/kg bw through subcutaneous administration of 2-Amino-4-methylpyridine.
- Executive summary:
The LD50 of mice is found to be 64 mg/kg bw through subcutaneous administration of 2-Amino-4-methylpyridine.
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