Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
basic toxicokinetics
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
other:

Description of key information

The toxicokinetic assessment of EAA is based on a weight of evidence approach and prepared based on the physico-chemical and toxicological studies being also part of this registration.

Key value for chemical safety assessment

Bioaccumulation potential:
no bioaccumulation potential

Additional information

The EAA toxicokinetic assessment is based on a weight of evidence approach: besides of the physico-chemical and toxicological studies of this dossier, the following references were included in the assessment:

- Deutsche Forschungsgemeinschaft (DFG): Toxikologisch-arbeitsmedizinische Begründung von MAK-Werten, Ethylacetat, 2000

- Deutsche Forschungsgemeinschaft (DFG): Toxikologisch-arbeitsmedizinische Begründung von MAK-Werten, Methylacetat, 2006

- Berufsgenossenschaft (BG) Chemie: Nr. 246 Acetessigsaeureethylester, 2004

- IUCLID database: Acetoacetate methylester (EAA), CAS 141 -97 -9