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EC number: 259-915-0 | CAS number: 55947-46-1
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
96 hrs aquatic toxicity study (SSS QSAR prediction model, 2016) was conducted to assess toxic effects of the test compound2-Propyne-1-sulfonic acid, sodium salt(CAS no 55947-46-1) and the results were predicted. The study was based on the effects of the test compound on the fish in a static fresh water system. The predicted data suggests the lethal concentration (LC50) for the test compound 2-Propyne-1-sulfonic acid, sodium salt was estimated to be 57.029315948 mg/L on the basis of mortality.
But the partition coefficient - Kow for the chemical was -2.16 which is less than criteria i.e 4 and bioaccumulation potential (BCF) also below criteria of 2000 i.e reported bioaccumulation value is 3.16 therefore the chemical was not considered for further classification.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 57.029 mg/L
Additional information
Various studies for the target chemical 2-Propyne-1-sulfonic acid, sodium salt and read across study were reviewed to summarize the following information:
96 hrs aquatic toxicity study (SSS QSAR prediction model, 2016) was conducted to assess toxic effects of the test compound 2-Propyne-1-sulfonic acid, sodium salt and the results were predicted. The study was based on the effects of the test compound on the fish in a static fresh water system. The predicted data suggests the lethal concentration (LC50) for the test compound 2-Propyne-1-sulfonic acid, sodium salt was estimated to be 57.029(CAS no 55947-46-1) 315948 mg/L on the basis of mortality.
But the partition coefficient - Kow for the chemical was -2.16 which is less than criteria i.e 4 therefore the chemical was considered as not classified as per CLP regulations.
Other predicted model for target chemical indicate that the lethal concentration (LC50) for the test compound2-Propyne-1-sulfonic acid, sodium salt was estimated to be 5500000 mg/l.
And read across substance sodium 2–methylprop–2–ene–1–sulphonate (1561-92-8) indicate that the during experiment the toxicity to fish LC0 value determined to be >= 100 mg/l on the basis of mortality effect.( IUCLID dataset; EUROPEAN COMMISSION European Chemicals Bureau,2000)
Same source for other read across Sodium vinylsulfonate (Cas no. 3039-83-6) shows the LC0 value to be > 500 mg/l on the basis of mortality effect.
Thus based on the various predicted and experimental studies the test substance 2-Propyne-1-sulfonic acid, sodium salt (CAS no 55947-46-1) consider to be non toxic to fish.
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