Registration Dossier
Registration Dossier
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EC number: 250-797-6 | CAS number: 31775-16-3
Solubility in organic solvents / fat solubility
Administrative data
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- January 4 - July 23, 1994
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study performed according to OECD guideline
Data source
Reference
- Title:
- Unnamed
- Year:
- 1 994
- Report date:
- 1994
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 116 (Fat Solubility of Solid and Liquid Substances)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[N-(4-methoxyphenyl)-3-oxobutyramide]
- EC Number:
- 250-797-6
- EC Name:
- 2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[N-(4-methoxyphenyl)-3-oxobutyramide]
- Cas Number:
- 31775-16-3
- Molecular formula:
- C34H30Cl2N6O6
- IUPAC Name:
- 2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[N-(4-methoxyphenyl)-3-oxobutyramide]
Constituent 1
Results and discussion
Solubility in organic solvents / fat solubility
- Medium:
- standard fat
- Remarks:
- HB 307
- Solubility:
- 0.006 other: g/kg
- Temp.:
- 37 °C
- Details on results:
- The preliminary test indicated the fat solubility to be 1.74 x 10-3 g/kg.
For results of the main test, see below.
Any other information on results incl. tables
Results of the main test:
Sample number |
Initial temperature |
Initial shaking time (hours) |
Final |
Final shaking time (hours) |
Concentration |
1 |
30 |
1½ |
37 |
3 |
5.75 x 10-3 |
2 |
30 |
1½ |
37 |
3 |
5.59 x 10-3 |
3 |
50 |
1½ |
37 |
3 |
7.01 x 10-3 |
4 |
50 |
1½ |
37 |
3 |
6.98 x 10-3 |
5 |
30 |
1¼ |
37 |
24¼ |
5.30 x 10-3 |
6 |
30 |
1¼ |
37 |
24¼ |
5.53 x 10-3 |
7 |
50 |
1¼ |
37 |
24¼ |
5.96 x 10-3 |
8 |
50 |
1¼ |
37 |
24¼ |
5.93 x 10-3 |
Mean concentration = 6.01 x 10-3 g/kg
Standard deviation = 6.47 x 10-4
Applicant's summary and conclusion
- Conclusions:
- The fat solubility of the test item is 6.01 x 10-3 g/kg at 37.0 °C.
- Executive summary:
The fat solubility of test substance has been determined in a guideline study to be 6.01 x 10-3 g/kg at 37.0 ± 0.5 °C.
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