Registration Dossier
Registration Dossier
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EC number: 700-156-6 | CAS number: 106649-95-0
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Referenceopen allclose all
- Reference Type:
- other: Predicted data
- Title:
- No information
- Author:
- Gedeon Richter Plc. Health and Safety Department
- Year:
- 2 015
- Bibliographic source:
- ChemProp - QSAR 6 Public OSIRIS Edition
- Reference Type:
- other: Predicted data
- Title:
- No information
- Author:
- Gedeon Richter Plc. Health and Safety Department
- Year:
- 2 015
- Bibliographic source:
- QSAR Toolbox 3.1.0.21
Materials and methods
Test guideline
- Guideline:
- other: REACH guidance on QSARs R.6, May/July2008
- GLP compliance:
- not specified
Test material
- Reference substance name:
- N-(aminosulfonyl)-3-chloropropanimidamide hydrochloride
- EC Number:
- 700-156-6
- Cas Number:
- 106649-95-0
- Molecular formula:
- C3H8ClN3O2S.HCl
- IUPAC Name:
- N-(aminosulfonyl)-3-chloropropanimidamide hydrochloride
Constituent 1
Results and discussion
Effect concentrations
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 4 774.985 mg/L
- Nominal / measured:
- estimated
Any other information on results incl. tables
- Sublethal observations / clinical signs:
Software Database / Method Endpoint Test duration Species Predicted value QSAR Toolbox Aquatic OASIS LC50 96 h Pimephales promales 1490 mg/l ChemProp Van Leeuwen et al model LC50 96 h Fathead minnow 8059.97 mg/l Inferential result 4774.985 mg/l
Applicant's summary and conclusion
- Conclusions:
- According to (Q)SAR modells: QSAR Toolbox, ChemProp the predicted values indicated that chlorosulfamidine hydrochloride is not hazardous to fishes. The result does not meet the requirement of any Aquatic Acute Category.
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