Registration Dossier
Registration Dossier
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EC number: 235-186-4 | CAS number: 12125-02-9
Endpoint summary
Administrative data
Description of key information
Based on the high water solubility and the ionic nature, ammonium chloride is not expected to adsorb or bioaccumulate to a significant extent. Ammonium (ammonia) is a naturally-occurring compound and a key intermediate in the nitrogen cycle. Since it is continually recycled, bioaccumulation, as it is usually considered, does not occur.
Additional information
In aqueous solution, ammonium chloride is completely dissociated into the ammonium ion (NH4+) and the chloride anion (Cl -). Depending on pH, ammonia (NH3) exists in equilibrium with the ammonium ion (NH4+), according to the following relationship:
NH4+ + H2O <-> NH3 + H3O+
Ammonia is ubiquitous in the aquatic environment as a consequence of the breakdown of plant and animal material and due to animal excretory processes. The generation of ammonia by normal metabolism (protein catabolism) occurs in all animal species, and therefore all animal species have developed effective physiological mechanisms of detoxification (metabolism to other nitrogenous compounds) or excretion. In fresh water fish, ammonia is excreted across the branchial epithelium via passive diffusion.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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