Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 208-534-8 | CAS number: 532-32-1
Immunotoxicity
Administrative data
Description of key information
In a publication (Cheung, 1984) effects of the testsubstance on fagocytosis of immunocomplexes by neutrophils was investigated. It was found that the test substance significantly reduces chemiluminisence, which is considered a representative for the strength of the fagocytosis, compared to the chemiluminisence found with untreated control cells.
Key value for chemical safety assessment
Additional information
The reference may discuss effects of the test substance on the non-specific part of immune system (fagocytosis), but is considered not sufficient to allow any conclusions.
Justification for classification or non-classification
Aggregated human gamma globulin (AHG) -induced chemiluminescence (CL) was suppressed in the presence of the test substance.
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