Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Only secondary source available. No data on test protocol, resulting LD50 only.

Data source

Reference
Reference Type:
secondary source
Title:
Toxicological Evaluations 12 - Potential Health Hazards of Existing Chemicals.
Author:
BG Chemie
Bibliographic source:
Toxicological Evaluations, volume 12, section "N,N'-di-sec-butyl-p-phenylenediamine", p. 193-203. Published by Springer.

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
N,N'-di-sec-butyl-p-phenylenediamine
EC Number:
202-992-2
EC Name:
N,N'-di-sec-butyl-p-phenylenediamine
Cas Number:
101-96-2
Molecular formula:
C14H24N2
IUPAC Name:
N,N'-di-sec-butyl-p-phenylenediamine

Test animals

Species:
rat
Strain:
Wistar
Sex:
not specified

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
not specified
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
> 10 - < 50 mg/kg bw
Based on:
test mat.
Clinical signs:
reeling, dyspnoea, poor general condition
Gross pathology:
intra-abdominal adhesions

Applicant's summary and conclusion