Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 244-754-0 | CAS number: 22047-49-0
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1985
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Comparable to guideline study with acceptable restrictions (analytical purity not specified, no necropsy performed, limited documentation).
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 985
- Report date:
- 1985
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 401 (Acute Oral Toxicity)
- Deviations:
- yes
- Remarks:
- analytical purity not specified, no necropsy performed, limited documentation
- GLP compliance:
- not specified
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- 2-ethylhexyl stearate
- EC Number:
- 244-754-0
- EC Name:
- 2-ethylhexyl stearate
- Cas Number:
- 22047-49-0
- Molecular formula:
- C26H52O2
- IUPAC Name:
- 2-ethylhexyl stearate
- Details on test material:
- - Name of test material (as cited in study report): Stearate D'Ethyl 2 Hexyl
- Physical state: no data
- Analytical purity: no data
- Lot/batch No.: 2826
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- other: NMRI EOPS
- Sex:
- male/female
- Details on test animals or test system and environmental conditions:
- TEST ANIMALS
- Weight at study initiation: 22 g (males) and 20 g (females)
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- unchanged (no vehicle)
- Doses:
- 4300 mg/kg bw (converted from 5 mL/kg bw, based on a density of 860 g/L)
- No. of animals per sex per dose:
- 5
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- male
- Dose descriptor:
- LD50
- Effect level:
- > 4 300 mg/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: no mortalities observed, converted from 5 mL/kg bw based on a density of 860 g/L, see IUCLID Section "Physical and chemical properties, Density"
- Mortality:
- No mortality occurred during the study period.
- Clinical signs:
- other: No clinical signs occurred during the study period.
Applicant's summary and conclusion
- Interpretation of results:
- practically nontoxic
- Remarks:
- Migrated information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
