Registration Dossier
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EC number: 232-164-6 | CAS number: 7789-41-5
Toxicity to birds
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
A read across approach from NaBr has shown bromide to be non-harmful to birds in acute toxicity studies at the limits of classification.
Read across from NaBr to CaBr2 is possible due to the full dissociation of both compounds in water. Na+ and Ca2+ are not toxic in the concentration ranges where Br- is toxic. Therefore only the Br- is responsible for the toxicity effects.
An acute toxicity test was conducted according to FIFRA guideline 71-1andASTM Standard E857-81. Bobwhite quail (Colinus virginianus) and mallard duck (Anas platyrhynchos) were given single oral doses of sodium bromide by gavage and monitored for 14 days afterwards – 10 birds per dose group were tested. No mortalities occurred in any dose groups of bobwhite quail. When compared to controls, there was no effect on body weight or feed consumption at any dosage level. Various signs of toxicity were observed in each dose groups at some point during the first week except the lowest dose and control groups. No signs persisted into the second week of observation. No mortalities occurred during the course of the study for mallard duck. Signs of toxicity typical of intoxication with sodium bromide included slight to severe ataxia (increasing with external stimuli), wing droop, lethargy, ventral head curl, and loss of righting reflex. When compared with the controls there was no effect on body weight or consumption at any of the concentrations tested. The 5-d LC50 > 5633 mg/kg sodium bromide for both species.
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