Registration Dossier
Registration Dossier
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EC number: 270-451-8 | CAS number: 68440-34-6
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (activated sludge, 3d) of 5.2mg Zn/L ; read-across
Key value for chemical safety assessment
Additional information
No studies are available on the short-term toxicity of Fatty acids, tallow, zinc salts to aquatic microorganisms. In accordance to Regulation (EC) No 1907/2006 Annex XI, 1.5, a read across to the structural analogue Fatty acids, C16-18, zinc salts (CAS No. 91051-01-3) and to inorganic zinc compounds was conducted. Based on similar structure, physico-chemical properties and zinc content, the ecotoxicological profile of the two substances is expected to be comparable. Further justification is given within the endpoint summary 6.1 and the analogue justification in section 13.
Fatty acids, C16 -18, zinc salts:
Two studies on microorganism toxicity are available for Fatty acids, C16 - 18, zinc salts. The first one was conducted according to the guideline DIN 38412, T34 (Luminescent Bacteria Inhibition Test) (TÜV, 1992). The test organism Photobacterium phosphoreum was exposed to the test substance for 30 minutes. The NOEC was determined to be 1560 mg/L. The second study was conducted according the guidelineDIN 38412, part 8 (Pseudomonas Zellvermehrungshemm-Test) (Berger, 1995). The test organism Pseudomonas putida was exposed to the test substance for 30 min. The NOEC was determined to be 1000 mg/L.
No toxicity of Fatty acids, C16 - 18, zinc salts to microorganisms is observed under the described test conditions, as also concluded in the EU Risk Assessment Report for the structural analogue Zinc distearate (CAS-No.: 557-05-1 and 91051-01-3; EINECS-No.: 209-151-9 and 293-049-4, Part 1 - Environment, Final report R074_0805_env, May 2008). Nevertheless the exposure duration is to short regarding current regulations. Therefore also data for inorganic Zinc compounds are taken into account.
ZINC:
Several data is available for this endpoint. The EC50 reported from the study by Dutka et al (1983), is giving the lowest reliable value of EC50 (3 h) = 5.2 mg/L.
For a comprehensive overview of the toxicity of zinc to microorganisms, see the hazard assessment of "Zinc" within the framework of Regulation (EC) No 1907/2006in the technical dossier (IUCLID section 13).
CONCLUSION:
Based on the above mentioned result of the studies conducted with Fatty acids, C16 - 18, zinc salts and inorganic Zinc compounds, the effect value of 5.2 mg/L is taken into account for Fatty acids, tallow, zinc salts.
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