Aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid complex

Endpoint summary

Description of key information

Biodegradation in water

Estimation Programs Interface Suite (EPI suite, 2017) was run to predict the biodegradation potential of the test compound  aluminium, 6 -hydroxy-5 -[(4 -sulfophenyl)azo]-2 -naphthalenesulfonic acid complex (CAS no.  15790 -07 -5) in the presence of mixed populations of environmental microorganisms. The biodegradability of the substance was calculated using seven different models such as Linear Model, Non-Linear Model, Ultimate Biodegradation Timeframe, Primary Biodegradation Timeframe, MITI Linear Model, MITI Non-Linear Model and Anaerobic Model (called as Biowin 1-7, respectively) of the BIOWIN v4.10 software. The results indicate that chemical aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid complex is expected to be not readily biodegradable.

Biodegradation in water and sediment

Estimation Programs Interface (EPI Suite, 2017) prediction model was run to predict the half-life in water and sediment for the test compound aluminium, 6 -hydroxy-5 -[(4 -sulfophenyl) azo]-2 -naphthalenesulfonic acid complex (CAS No. 15790 -07 -5). If released in to the environment, 8.77% of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid complex in water is estimated to be 60 days (1440 hrs). The half-life (60 days estimated by EPI suite) indicates that the chemical is persistent in water and the exposure risk to aquatic animals is moderate to high whereas the half-life period of aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid complex in sediment is estimated to be 541.66 days (13000 hrs). However, as the percentage release of test chemical into the sediment is less than 2% (i.e, reported as 1.53%), indicates that aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid complex is not persistent in sediment.

Biodegradation in soil

The half-life period of aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid complex (CAS No. 15790 --07 -5) in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (EPI suite, 2017). If released into the environment, 89.7% of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid complex in soil is estimated to be 120 days (2880 hrs). Based on this half-life value of aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid complex, it is concluded that the chemical is not persistent in the soil environment and the exposure risk to soil dwelling animals is moderate to low..

Additional information

Biodegradation in water

Predicted data for the target compound aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid complex (CAS No. 15790-07-5) and various supporting weight of evidence studies for its read across substance were reviewed for the biodegradation end point which are summarized as below:

 

In a prediction done using the Estimation Programs Interface Suite (EPI suite, 2017), the biodegradation potential of the test compoundaluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid complex(CAS No. 15790-07-5) in the presence of mixed populations of environmental microorganisms was estimated.The biodegradability of the substance was calculated using seven different models such as Linear Model, Non-Linear Model, Ultimate Biodegradation Timeframe, Primary Biodegradation Timeframe, MITI Linear Model, MITI Non-Linear Model and Anaerobic Model (called as Biowin 1-7, respectively) of the BIOWIN v4.10 software. The results indicate that chemicalaluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid complexis expected to be not readily biodegradable.

 

In a supporting weight of evidence study from peer reviewed journal (Yasuhide TONOGAI et. al, 1978) for read across substancetrisodium (4E)-3-oxo-4-[2-(4-sulfonatonaphthalen-1-yl)hydrazin-1-ylidene]-3,4-dihydronaphthalene-2,7-disulfonate (CAS no. 915-67-3),biodegradation study was conducted under aerobic conditions for evaluating the percentage biodegradability of read across substance trisodium (4E)-3-oxo-4-[2-(4-sulfonatonaphthalen-1-yl)hydrazin-1-ylidene]-3,4-dihydronaphthalene-2,7-disulfonate. Activated sludge was used as a test inoculum obtained from the municipal sewage treatment plant, Nakahama, Osaka. The return sludge was acclimated to the synthetic sewage for a week or longer, and it was used for the aerobic and anaerobic decomposition experiments. Synthetic sewage was prepared by dissolving Glucose, peptone and potassium dihydrogen phosphate, 30g each, in 1 liter water and the pH was adjusted to pH 7.0 with sodium hydroxide. Concentration of inoculum used for the study was3000 mg/l. Percentage degradation of chemical was determined by measuring the absorbance (test material analysis), oxygen uptake and BOD parameter. For the aerobic decomposition of dyes with sludge, 250 ml of O.03 M dye solution was added to 750ml of sludge (MLSS ca, 3,000 ppm), and bubbled with air sufficiently at 20°C. 5ml sample was taken out once a day. After sampling 5ml of synthetic sewage was added to the mixture. Each sample was filtered through filter paper and diluted twenty times prior to the spectrophotometric measurement at the absorption maximum within the visible range. The decrease of dyes concentration was expressed in terms of percent to the initial absorption whereas measurement oxygen uptake by sludge involve 2.0 ml of sludge, 0.2 ml of 1,000 ppm dye solution, and O.2 ml of 20% potassium hydroxide were pipetted into the vessel, the side arm and central well, respectively. The sludge and the dye solution were mixed and the vessel was shaken at 25"C. The oxygen uptake was measured. The oxygen uptake by sludge alone was subtracted from the dye addition. For determining the BOD values, test chemical solutions (10, 20 and 40 ppm) were prepared with the seeded dilution water and kept at 20°C. The dissolved oxygen contents were then measured by using a dissolved oxygen meter. The percentage degradation of test chemicaltrisodium (4E)-3-oxo-4-[2-(4-sulfonatonaphthalen-1-yl)hydrazin-1-ylidene]-3,4-dihydronaphthalene-2,7-disulfonatewas determined to be 20% in 10 days by using the test material analysis parameter. From the oxygen uptake by Warburg’s manometer, the low activity of the sludge to dye was obtained and by using the dissolved oxygen meter, the dissolved oxygen contents on the 5th day were essentially the same to initial ones. Thus, based on percentage degradation, the chemical trisodium (4E)-3-oxo-4-[2-(4-sulfonatonaphthalen-1-yl)hydrazin-1-ylidene]-3,4-dihydronaphthalene-2,7-disulfonate was considered to be not readily biodegradable in nature.

 

Another biodegradation study was conducted for 5 days for evaluating the percentage biodegradability of read across substance disodium (5E)-6 -oxo-5 -[(4 -sulfonatophenyl)hydrazinylidene]naphthalene-2 -sulfonate (CAS no. 2783 -94 -0) under aerobic conditions (HSDB, 2017). Sewage was used as a test inoculum for the study. The percentage degradation of test substance disodium (5E)-6-oxo-5-[(4-sulfonatophenyl)hydrazinylidene]naphthalene-2-sulfonatewas determined to be 0% by using BOD parameter in 5 days. Thus, based on percentage degradation,disodium (5E)-6-oxo-5-[(4-sulfonatophenyl)hydrazinylidene]naphthalene-2-sulfonateis considered to be not readily biodegradable in water.

 

For the read across chemical calcium 3-hydroxy-4-[(4-methyl-2-sulfonatophenyl)diazenyl]-2-naphthoate (CAS no. 5281-04-9) from authoritative database (J-CHECK, 2017) and secondary source (HPVIS and OECD SIDS), biodegradation experiment was conducted for 28 days for evaluating the percentage biodegradability of read across substance calcium 3 -hydroxy-4 -[(4 -methyl-2 -sulfonatophenyl)diazenyl]-2 -naphthoate (CAS no. 5281 -04 -9). The study was performed according to OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I) under aerobic conditions. Activated sludge (non-adapted) was used as a test inoculums for the study. Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l, respectively. The percentage degradation of substance calcium 3 -hydroxy-4 -[(4 -methyl-2 -sulfonatophenyl)diazenyl]-2 -naphthoate was determined to be 10 and 0% by BOD and HPLC parameter in 28 days. Thus, based on percentage degradation, calcium 3-hydroxy-4-[(4-methyl-2-sulfonato phenyl)diazenyl]-2-naphthoate is considered to be not readily biodegradable in nature.

 

On the basis of above results for target chemical aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid complex (EPI suite, 2017) and for its read across substance (from peer reviewed journal, authoritative database J-CHECK & HSDB and secondary source HPVIS & OECD SIDS), it can be concluded that the test substance aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid complexcan be expected to be not readily biodegradable in nature.

Biodegradation in water and sediment

Estimation Programs Interface (EPI Suite, 2017) prediction model was run to predict the half-life in water and sediment for the test compound aluminium, 6 -hydroxy-5 -[(4 -sulfophenyl) azo]-2 -naphthalenesulfonic acid complex (CAS No. 15790 -07 -5). If released in to the environment, 8.77% of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid complex in water is estimated to be 60 days (1440 hrs). The half-life (60 days estimated by EPI suite) indicates that the chemical is persistent in water and the exposure risk to aquatic animals is moderate to high whereas the half-life period of aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid complex in sediment is estimated to be 541.66 days (13000 hrs). However, as the percentage release of test chemical into the sediment is less than 2% (i.e, reported as 1.53%), indicates that aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid complex is not persistent in sediment.

Biodegradation in soil

The half-life period of aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid complex (CAS No. 15790 --07 -5) in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (EPI suite, 2017). If released into the environment, 89.7% of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid complex in soil is estimated to be 120 days (2880 hrs). Based on this half-life value of aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid complex, it is concluded that the chemical is not persistent in the soil environment and the exposure risk to soil dwelling animals is moderate to low..

On the basis of available information, the test substance aluminium, 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid complex can be considered to be not readily biodegradable in nature.