Registration Dossier
Registration Dossier
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EC number: 203-851-8 | CAS number: 111-26-2
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: sufficient for classification with restrictions (short exposure times)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 969
- Report date:
- 1969
Materials and methods
- Principles of method if other than guideline:
- according to BASF-internal standard
- GLP compliance:
- no
- Test type:
- other: inhalation hazard test
Test material
- Reference substance name:
- Hexylamine
- EC Number:
- 203-851-8
- EC Name:
- Hexylamine
- Cas Number:
- 111-26-2
- Molecular formula:
- C6H15N
- IUPAC Name:
- hexan-1-amine
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- male/female
Administration / exposure
- Route of administration:
- inhalation: vapour
- Type of inhalation exposure:
- not specified
- Vehicle:
- not specified
- Analytical verification of test atmosphere concentrations:
- not specified
- Remarks on duration:
- 3 min and 10 min
- Concentrations:
- 74.67 mg/L
- No. of animals per sex per dose:
- 3 min: 12
10 min: 6 - Control animals:
- not specified
Results and discussion
Effect levelsopen allclose all
- Sex:
- male/female
- Dose descriptor:
- LC0
- Effect level:
- 74.67 mg/L air
- Based on:
- test mat.
- Exp. duration:
- 3 min
- Sex:
- male/female
- Dose descriptor:
- LC50
- Effect level:
- < 74.67 mg/L air
- Based on:
- test mat.
- Exp. duration:
- 10 min
- Mortality:
- 3 min exposure: no deaths
10 min exposure: 5/6 - Clinical signs:
- other: severe attempt to escape, intense reddening of the mucosa, dyspnea, breathlessness, at the end of the study trembling
- Body weight:
- no data
- Gross pathology:
- bloody-serous blurred snouts, cloudings of the breaking media of the eyes
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
