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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
other: Expert assessment
Adequacy of study:
key study
Study period:
May 2021
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: An assessment was performed based on the predictive model PetroTox and for the other polar constituents, a combination of available data in literature and the use of QSAR modelling with ECOSAR (2.0)
Qualifier:
no guideline required
Principles of method if other than guideline:
An assessment was performed based on the predictive model PetroTox and for the other polar constituents, a combination of available data in literature and the use of QSAR modelling with ECOSAR (2.0)
GLP compliance:
no
Key result
Duration:
96 h
Dose descriptor:
other: LC50
Effect conc.:
4.85 mg/L
Conc. based on:
other: hydrocarbon fraction
Key result
Duration:
96 h
Dose descriptor:
other: LC50
Effect conc.:
30 mg/L
Conc. based on:
other: polar fraction
Details on results:
See attached expert assessment
Conclusions:
The predicted acute toxicity (LC50) of Thermal cracking oil from blends of rubber, fuel oils and paraffin waxes, steam distillation condensate to algae is predicted to be 30 mg/L on the
basis of polar fraction and 4.85 mg/L on the basis of hydrocarbon fraction. Hence, an LL50
of 4.85 mg/L can be considered as the acute toxicity value of the substance in algae.
Executive summary:

Thermal cracking oil from blends of rubber, fuel oils and paraffin waxes, steam distillation condensate (EC 942-492-8) is a complex UVCB consisting of a combination of different hydrocarbon constituents with a range of different molecular weights and structures. As toxicity test data to aquatic algae and cyanobacteria for the substance was not available, QSAR modelling was used to assess the toxicity to algae (Pseudokirchneriella subcapitata) for this substance.
For the hydrocarbon fraction the predictive model PetroTox, made available by CONCAWE was used, and for the other polar constituents, a combination of available data in literature and the use of QSAR modelling with ECOSAR (2.0) from the EPA was used.


The predicted acute toxicity (LC50) of Thermal cracking oil from blends of rubber, fuel oils and paraffin waxes, steam distillation condensate to algae is predicted to be 30 mg/L on the basis of polar fraction and 4.85 mg/L on the basis of hydrocarbon fraction. Hence, an LL50 of 4.85 mg/L can be considered as the acute toxicity value of the substance in algae.

Description of key information

Thermal cracking oil from blends of rubber, fuel oils and paraffin waxes, steam distillation condensate (EC 942-492-8) is a complex UVCB consisting of a combination of different hydrocarbon constituents with a range of different molecular weights and structures. As toxicity test data to aquatic algae and cyanobacteria for the substance was not available, QSAR modelling was used to assess the toxicity to algae (Pseudokirchneriella subcapitata) for this substance.


The predicted acute toxicity (LC50) of naphtha to algae is predicted to be 30 mg/L on the basis of polar fraction and 4.85 mg/L on the basis of hydrocarbon fraction. Hence, an LL50 of 4.85 mg/L can be considered as the acute toxicity value of naphtha in algae.

Key value for chemical safety assessment

EC50 for freshwater algae:
4.85 mg/L

Additional information