1,2-Pyrrolidinedicarboxylic acid, 4-oxo-, 1-(1,1-dimethylethyl) ester, (2S)-

Auto flammability

Administrative data

Endpoint:

relative self-ignition temperature (solids)

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2015_01_09 - 2015_01_16

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

comparable to guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2015

Report date:

2015

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: UN Recommendation on the TRANSPORT OF DANGEROUS GOODS: Manual of Tests and Criteria, Rev. 6 (2015) and UN-Model_Regulations, Rev. 19 (2015), \/Dl 2263 Sheet 1, Grewer-Oven (1990)

Deviations:

no

GLP compliance:

not specified

Test material

Test material information

Constituent 1

Reference substance name:

(2S)-1-(tert-butoxycarbonyl)-4-oxopyrrolidine-2-carboxylic acid

EC Number:

617-556-0

Cas Number:

84348-37-8

Molecular formula:

C10H15NO5

IUPAC Name:

(2S)-1-(tert-butoxycarbonyl)-4-oxopyrrolidine-2-carboxylic acid

Test material form:

solid: crystalline

Results and discussion

Relative self-ignition temperature (solids)

Key result

Relative self-ignition temperature:

>= 190 °C

Remarks on result:

preliminary test

Remarks:

Strongly exothermic behaviour can be observed from a temperature of 190°C; further tests would be necessary

Any other information on results incl. tables

Results:

UN-Transport class 4.2 „self-heating substances“

After an endothermic reaction in the range of approx. 150°C – approx. 180°, a strongly exothermic behaviour can be observed from a temperature of 190°C. The measured temperature increase compared to the thermally inert reference sample (graphite powder) was about 185 K (- 88.15 °C).
In the UN Manual "Transport of Dangerous Goods, Manual of Tests & Criteria", Appendix 6, Chapter 5.2.2, the Grewer Oven Test is specified as a screening method for UN transport class 4.2. With this initial test, it can first be evaluated whether the sample is even suitable as a candidate for class 4.2 or not. If the onset temperature determined in air atmosphere for an exothermic reaction of the sample is >220 °C, further tests for class 4.2 are no longer required. The substance then does not meet the conditions of transport class 4.2. Due to the onset temperature determined here, further tests would be necessary with regard to this transport class.

 

Additional test with nitrogen:
The examination of the sample under an inert atmosphere (pure nitrogen), on the other hand, showed no exothermic effects up to the maximum test temperature of approx. 480 °C. An exothermic decomposition reaction can thus be clearly ruled out. For self-heating, atmospheric oxygen is mandatory. Since no exothermia occurred during the experiment in the Grewer Oven under nitrogen atmosphere, the input criterion of the aforementioned transport class is not met. The investigated substance does not meet the conditions of UN transport class 4.1 "self-reactive substances".

Applicant's summary and conclusion

Conclusions:

Further tests would be necessary.