Antimony, mixed dipentyldithiocarbamate and bis(2-ethylhexyl)dithiocarbamate complexes

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

21 February 2018 - 25 October 2018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

GLP compliance:

yes

Type of method:

method to determine freezing temperature

Specific details on test material used for the study:

Physical state: Clear amber liquid
Stability under storage conditions: Stable at room temperature
Storage condition of test material: Ambient

Key result

Melting / freezing pt.:

< -20 °C

Remarks on result:

other: The study does not need to be conducted below alover limit of -20 Deg.C

 Freezing Point Observations

Temperature	Sample Appearance
4 °C	Test Item mobile upon inversion of vial, i.e. not frozen
-20 °C	Test Item mobile upon inversion of vial, i.e. not frozen
-80 °C	Test Item less fluid than -20 °C but still mobile, i.e. not frozen

The preliminary test indicates a freezing point of < -20 °C for the Test Item. Therefore, a full freezing point determination is not required as described in ECHA Guidance R.7.1.2:

Column 2 of REACH Annex VII provides the following specific rules for adaptation of the standard information requirement for melting point/freezing point:

‘The study does not need to be conducted below a lower limit of -20 °C.’

‘Therefore, Annex 7 to REACH does not require determination of the melting point below a lower limit of -20 °C. The lower limit should be confirmed through testing, except where a (Q)SAR indicates a melting point of -50 °C or lower.’

Conclusions:

In an EU Method A.1 study, conducted according to GLP, the freezing temperature of the substance was determined to be <-20°C (Intertek Pharmaceutical Services, 2018).

Executive summary:

The preliminary test indicates a freezing point of < -20 °C for the Test Item. Therefore, a full freezing point determination is not required.

In an EU Method A.1 study, conducted according to GLP, the freezing temperature of the substance was determined to be <-20°C (Intertek Pharmaceutical Services, 2018).

Description of key information

In an EU Method A.1 study, conducted according to GLP, the freezing temperature of the substance was determined to be <-20°C (Intertek Pharmaceutical Services, 2018).

Key value for chemical safety assessment

Additional information

In an EU Method A.1 study, conducted according to GLP, the freezing point of the test material is < -20°C (Intertek Pharmaceutical Services, 2018).