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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

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Key value for chemical safety assessment

Additional information

Justification for classification or non-classification

In order to evaluate toxicological properties of the substance erbium tetraoxide vanadium, information on the assessment entities erbium ions (i.e. erbium oxide) and vanadium ions were considered. For a documentation and justification of that approach, please refer to the separate document attached to section 13, namely Read Across Assessment Report for erbium tetraoxide vanadium.

The toxicity of erbium tetraoxide vanadium may reasonably be considered to be determined by the bioavailability of the assessment entity "vanadium ions" since there are not any indications that the assessment entity “erbium ions” (i.e. erbium oxide) would be classified as hazardous for human health under Regulation (EC) No 1272/2008. Based on the available weight-of-evidence, and considering guideline-conform studies conducted under GLP both in vitro as well as in vivo, vanadium ions should be considered void of genotoxicity. Similarly, classification of erbium tetraoxide vanadium with respect to a mutagenic potential does not appear to be supported. Thus, according to EC Regulation No. 1272/2008, erbium tetraoxide vanadium should not be considered to have a mutagenic potential, and hence classification or labelling is not required.