Registration Dossier
Registration Dossier
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EC number: 228-711-3 | CAS number: 6334-18-5
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- in vitro gene mutation study in bacteria
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
Data source
Reference
- Reference Type:
- secondary source
- Title:
- Mutagenicity of chlorinated aromatic hydrocarbons containing oxygen
- Author:
- Ohkubo, T; Goto, S; Endo, O; Hayashi, T; Watanabe, E; Endo, H
- Year:
- 1 996
- Bibliographic source:
- Kankyo Kagaku 6(4): 533-540
Materials and methods
- Type of assay:
- bacterial reverse mutation assay
Test material
- Reference substance name:
- 2,3-dichlorobenzaldehyde
- EC Number:
- 228-711-3
- EC Name:
- 2,3-dichlorobenzaldehyde
- Cas Number:
- 6334-18-5
- Molecular formula:
- C7H4Cl2O
- IUPAC Name:
- 2,3-dichlorobenzaldehyde
- Test material form:
- solid: crystalline
- Details on test material:
- Test item: 2,3-dichlorobenzaldehydeCas No.: 6334-18-5Storage: 15-30 °C
Constituent 1
Method
Species / strainopen allclose all
- Species / strain / cell type:
- S. typhimurium TA 98
- Species / strain / cell type:
- S. typhimurium TA 100
- Species / strain / cell type:
- S. typhimurium, other: 104
- Species / strain / cell type:
- E. coli WP2 uvr A
- Metabolic activation:
- with and without
- Metabolic activation system:
- rat liver S-9, PCB
Results and discussion
Test resultsopen allclose all
- Species / strain:
- S. typhimurium TA 98
- Metabolic activation:
- with and without
- Genotoxicity:
- negative
- Cytotoxicity / choice of top concentrations:
- not determined
- Species / strain:
- S. typhimurium TA 100
- Metabolic activation:
- with and without
- Genotoxicity:
- negative
- Cytotoxicity / choice of top concentrations:
- not determined
- Species / strain:
- S. typhimurium, other: 104
- Metabolic activation:
- with and without
- Genotoxicity:
- negative
- Cytotoxicity / choice of top concentrations:
- not determined
- Species / strain:
- E. coli WP2 uvr A
- Metabolic activation:
- with and without
- Genotoxicity:
- negative
- Cytotoxicity / choice of top concentrations:
- not determined
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
