Registration Dossier
Registration Dossier
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EC number: 204-614-1 | CAS number: 123-28-4
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Study period:
- 1954
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: non GLP, no individual data, test item was from a pilot process.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 954
- Report date:
- 1954
Materials and methods
Test guideline
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- 22 Mice were treated subcutanously with various doses of the test item.
- Limit test:
- no
Test material
- Reference substance name:
- Didodecyl 3,3'-thiodipropionate
- EC Number:
- 204-614-1
- EC Name:
- Didodecyl 3,3'-thiodipropionate
- Cas Number:
- 123-28-4
- Molecular formula:
- C30H58O4S
- IUPAC Name:
- didodecyl 3,3'-sulfanediyldipropanoate
- Details on test material:
- Was supplied by Dr.Ehrmann, Hauptlabor ZK Gruppe.
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- subcutaneous
- Vehicle:
- other: oil
- Details on exposure:
- single treatment with 25% of the test substance in oil
- Doses:
- 2, 4, 8, 16 g/kg bw
- No. of animals per sex per dose:
- 1 (2, 4 g/kg); 10 (8, 16 g/kg)
- Control animals:
- not specified
- Details on study design:
- no data
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 16 000 mg/kg bw
- Remarks on result:
- other: one animal died within 6 days post treatment
- Mortality:
- 16000 mg/kg: one animal died within 6 days post treatment, no mortalities in the other groups.
- Clinical signs:
- Ruffled fur.
No findings in surviving animals. - Body weight:
- no data
- Gross pathology:
- no data
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
