Registration Dossier
Registration Dossier
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EC number: 268-771-8 | CAS number: 68140-01-2
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2019
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- publication
- Title:
- Fatty acid amido propyl dimethylamines: Human health tier II Assessment
- Author:
- NICNAS
- Year:
- 2 019
- Bibliographic source:
- NICNAS Health Assessment
- Report date:
- 2019
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- not specified in the NICNAS report
- GLP compliance:
- not specified
- Remarks:
- Not specified in the NICNAS report
- Test type:
- other: not specified
Test material
- Reference substance name:
- Amides, coco, N-[3-(dimethylamino)propyl]
- EC Number:
- 268-771-8
- EC Name:
- Amides, coco, N-[3-(dimethylamino)propyl]
- Cas Number:
- 68140-01-2
- IUPAC Name:
- Amines, C12-18, alkyldimethyl
- Test material form:
- liquid
Constituent 1
Test animals
- Species:
- rat
Administration / exposure
- Route of administration:
- oral: drinking water
- Vehicle:
- unchanged (no vehicle)
- Control animals:
- not specified
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- >= 300 - <= 2 000 mg/kg bw
- Based on:
- test mat.
Applicant's summary and conclusion
- Interpretation of results:
- Category 4 based on GHS criteria
- Remarks:
- H302 Harmful if swallowed
- Conclusions:
- Cocamidopropyl Dimethylamine : Oral Acute Toxicity : LD 50 : 300 - 2000 mg/kg bw
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