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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
fish early-life stage toxicity
Data waiving:
exposure considerations
Justification for data waiving:
other:
Cross-referenceopen allclose all
Reason / purpose for cross-reference:
data waiving: supporting information
Reference
Registration/ Notification status for the use:
use registered according to REACH Article 10; total tonnage manufactured/imported >=10tonnes/year per registrant
Use name:
Use as intermediate in the manufacture of other substances (squalane)
Name of activity / technique:
Use as intermediate in the manufacture of other substances (squalane)
Environmental release category (ERC):
ERC6a: Use of intermediate
Name of activity / technique:
Closed process without likelihood of exposure
Process category (PROC):
PROC 1: Chemical production or refinery in closed process without likelihood of exposure or processes with equivalent containment conditions
Name of activity / technique:
Closed continuous process with occasional controlled exposure
Process category (PROC):
PROC 2: Chemical production or refinery in closed continuous process with occasional controlled exposure or processes with equivalent containment conditions
Name of activity / technique:
Closed batch process with occasional controlled exposure
Process category (PROC):
PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
Name of activity / technique:
Transfer of the substance at dedicated facilities
Process category (PROC):
PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
Name of activity / technique:
Transfer of substance or mixture into small containers
Process category (PROC):
PROC 9: Transfer of substance or mixture into small containers (dedicated filling line, including weighing)
Name of activity / technique:
Laboratory analysis of samples
Process category (PROC):
PROC 15: Use as laboratory reagent
Substance supplied to that use in form of:
as such
Subsequent service life relevant for this use:
no
Related assessment:
use assessed in an own CSR
Linked contributing activity:
01710c11-e21d-4639-bd3b-cb21416ab2c9
Biological Sewage Treatment Plant (STP):
no
Particular considerations on the waste treatment operations:
no
Receiving surface water flow rate (m³/day):
18 000
Other conditions of use impacting on environmental exposure:
Discharge rate of effluent: >= 2E3 m3/day
Release from the site to::
surface water
Release estimation method:
estimated release factor
Remarks:
Industry-specific
Release factor from the site after on-site risk management (%):
0
Release from the site to::
ambient air
Release estimation method:
estimated release factor
Remarks:
Industry-specific
Release factor from the site after on-site risk management (%):
0
Release from the site to::
non-agricultural soil
Release estimation method:
estimated release factor
Remarks:
Industry-specific
Release factor from the site after on-site risk management (%):
0
Release factor to external waste (%):
0
Exposed compartment:
freshwater
Clocal:
0 mg/L
Predicted exposure concentration:
0 mg/L
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Version of exposure estimation tool:
2.1.2
Exposed compartment:
sediment (freshwater)
Predicted exposure concentration:
0 mg/kg dw
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Version of exposure estimation tool:
2.1.2
Exposed compartment:
marine water
Clocal:
0 mg/L
Predicted exposure concentration:
0 mg/L
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Version of exposure estimation tool:
2.1.2
Exposed compartment:
sediment (marine water)
Predicted exposure concentration:
0 mg/kg dw
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Version of exposure estimation tool:
2.1.2
Exposed compartment:
sewage treatment plant
Predicted exposure concentration:
0 mg/L
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Version of exposure estimation tool:
2.1.2
Exposed compartment:
air
Clocal:
0 mg/m³
Predicted exposure concentration:
0 mg/m³
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Version of exposure estimation tool:
2.1.2
Exposed compartment:
agricultural soil
Clocal:
0 mg/kg dw
Predicted exposure concentration:
0 mg/kg dw
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Version of exposure estimation tool:
2.1.2
Exposed compartment:
predators' prey (freshwater)
Predicted exposure concentration:
0 mg/kg ww
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Version of exposure estimation tool:
2.1.2
Exposed compartment:
predators' prey (marine water)
Predicted exposure concentration:
0 mg/kg ww
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Version of exposure estimation tool:
2.1.2
Exposed compartment:
top predators' prey (marine water)
Predicted exposure concentration:
0 mg/kg ww
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Version of exposure estimation tool:
2.1.2
Exposed compartment:
predators' prey (terrestrial)
Predicted exposure concentration:
0 mg/kg ww
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Version of exposure estimation tool:
2.1.2
Daily intake via food consumption:
0 mg/kg bw/day
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
EUSES
Version of exposure estimation tool:
2.1.2
Linked contributing activity:
c55aa072-b928-4f08-956e-be488769fc85
Percentage (w/w) of substance in mixture/article:
100
Physical form of the used product:
liquid, including paste/slurry/suspension
Duration of activity (hour/day):
8
Technical and organisational conditions and measures:
General ventilation: Basic general ventilation (1-3 air changes per hour)
Effectiveness (%):
0
Route affected:
inhalation
Technical and organisational conditions and measures:
Occupational Health and Safety Management System: Advanced
Technical and organisational conditions and measures:
Local exhaust ventilation: No
Effectiveness (%):
0
Route affected:
inhalation
Effectiveness (%):
0
Route affected:
dermal
Personal protection equipment:
Respiratory protection: No
Effectiveness (%):
0
Route affected:
inhalation
Personal protection equipment:
Dermal protection: No
Effectiveness (%):
0
Route affected:
dermal
Place of use:
indoor
Operating temperature (°C):
40
Type of exposure:
inhalation (external) long-term exposure
Exposure estimate:
0.208 mg/m³
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers
Version of exposure estimation tool:
3.0
Type of exposure:
inhalation (external) short-term exposure
Exposure estimate:
0.208 mg/m³
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers
Version of exposure estimation tool:
3.0
Type of exposure:
dermal (external) long-term exposure
Exposure estimate:
0.034 mg/kg bw/day
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers
Version of exposure estimation tool:
3.0
Linked contributing activity:
62f9ad30-937e-46a0-939f-d99b683975da
Percentage (w/w) of substance in mixture/article:
100
Physical form of the used product:
liquid, including paste/slurry/suspension
Duration of activity (hour/day):
8
Technical and organisational conditions and measures:
General ventilation: Basic general ventilation (1-3 air changes per hour)
Effectiveness (%):
0
Route affected:
inhalation
Technical and organisational conditions and measures:
Occupational Health and Safety Management System: Advanced
Technical and organisational conditions and measures:
Local exhaust ventilation: No
Effectiveness (%):
0
Route affected:
inhalation
Effectiveness (%):
0
Route affected:
dermal
Personal protection equipment:
Respiratory protection: No
Effectiveness (%):
0
Route affected:
inhalation
Personal protection equipment:
Dermal protection: No
Effectiveness (%):
0
Route affected:
dermal
Place of use:
indoor
Operating temperature (°C):
40
Type of exposure:
inhalation (external) long-term exposure
Exposure estimate:
2.083 mg/m³
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers
Version of exposure estimation tool:
3.0
Type of exposure:
inhalation (external) short-term exposure
Exposure estimate:
2.083 mg/m³
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers
Version of exposure estimation tool:
3.0
Type of exposure:
dermal (external) long-term exposure
Exposure estimate:
1.37 mg/kg bw/day
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers
Version of exposure estimation tool:
3.0
Linked contributing activity:
49b22a54-be7e-4a72-b57e-5d7425954ccf
Percentage (w/w) of substance in mixture/article:
100
Physical form of the used product:
liquid, including paste/slurry/suspension
Duration of activity (hour/day):
8
Technical and organisational conditions and measures:
General ventilation: Basic general ventilation (1-3 air changes per hour)
Effectiveness (%):
0
Route affected:
inhalation
Technical and organisational conditions and measures:
Occupational Health and Safety Management System: Advanced
Technical and organisational conditions and measures:
Local exhaust ventilation: No
Effectiveness (%):
0
Route affected:
inhalation
Effectiveness (%):
0
Route affected:
dermal
Personal protection equipment:
Respiratory protection: No
Effectiveness (%):
0
Route affected:
inhalation
Personal protection equipment:
Dermal protection: No
Effectiveness (%):
0
Route affected:
dermal
Place of use:
indoor
Operating temperature (°C):
40
Type of exposure:
inhalation (external) long-term exposure
Exposure estimate:
2.083 mg/m³
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers
Version of exposure estimation tool:
3.0
Type of exposure:
inhalation (external) short-term exposure
Exposure estimate:
2.083 mg/m³
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers
Version of exposure estimation tool:
3.0
Type of exposure:
dermal (external) long-term exposure
Exposure estimate:
0.69 mg/kg bw/day
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers
Version of exposure estimation tool:
3.0
Linked contributing activity:
6e475610-dca6-41de-85d4-6254f819e10a
Percentage (w/w) of substance in mixture/article:
100
Physical form of the used product:
liquid, including paste/slurry/suspension
Duration of activity (hour/day):
8
Technical and organisational conditions and measures:
General ventilation: Basic general ventilation (1-3 air changes per hour)
Effectiveness (%):
0
Route affected:
inhalation
Technical and organisational conditions and measures:
Occupational Health and Safety Management System: Advanced
Technical and organisational conditions and measures:
Local exhaust ventilation: No
Effectiveness (%):
0
Route affected:
inhalation
Effectiveness (%):
0
Route affected:
dermal
Personal protection equipment:
Respiratory protection: No
Effectiveness (%):
0
Route affected:
inhalation
Personal protection equipment:
Dermal protection: Yes (Chemically resistant gloves conforming to EN374) and (other) appropriate dermal protection
Effectiveness (%):
80
Route affected:
dermal
Place of use:
indoor
Operating temperature (°C):
40
Type of exposure:
inhalation (external) long-term exposure
Exposure estimate:
2.083 mg/m³
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers
Version of exposure estimation tool:
3.0
Type of exposure:
inhalation (external) short-term exposure
Exposure estimate:
2.083 mg/m³
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers
Version of exposure estimation tool:
3.0
Type of exposure:
dermal (external) long-term exposure
Exposure estimate:
2.742 mg/kg bw/day
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers
Version of exposure estimation tool:
3.0
Linked contributing activity:
908f15ff-2afa-4c8b-acb9-dc02866e4583
Percentage (w/w) of substance in mixture/article:
100
Physical form of the used product:
liquid, including paste/slurry/suspension
Duration of activity (hour/day):
8
Technical and organisational conditions and measures:
General ventilation: Basic general ventilation (1-3 air changes per hour)
Effectiveness (%):
0
Route affected:
inhalation
Technical and organisational conditions and measures:
Occupational Health and Safety Management System: Advanced
Technical and organisational conditions and measures:
Local exhaust ventilation: No
Effectiveness (%):
0
Route affected:
inhalation
Effectiveness (%):
0
Route affected:
dermal
Personal protection equipment:
Respiratory protection: No
Effectiveness (%):
0
Route affected:
inhalation
Personal protection equipment:
Dermal protection: Yes (Chemically resistant gloves conforming to EN374) and (other) appropriate dermal protection
Effectiveness (%):
80
Route affected:
dermal
Place of use:
indoor
Operating temperature (°C):
40
Type of exposure:
inhalation (external) long-term exposure
Exposure estimate:
2.083 mg/m³
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers
Version of exposure estimation tool:
3.0
Type of exposure:
inhalation (external) short-term exposure
Exposure estimate:
2.083 mg/m³
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers
Version of exposure estimation tool:
3.0
Type of exposure:
dermal (external) long-term exposure
Exposure estimate:
1.372 mg/kg bw/day
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers
Version of exposure estimation tool:
3.0
Linked contributing activity:
adbb84a9-50b8-410f-bd42-b1f3f52e980e
Percentage (w/w) of substance in mixture/article:
100
Physical form of the used product:
liquid, including paste/slurry/suspension
Duration of activity (hour/day):
8
Technical and organisational conditions and measures:
General ventilation: Basic general ventilation (1-3 air changes per hour)
Effectiveness (%):
0
Route affected:
inhalation
Technical and organisational conditions and measures:
Occupational Health and Safety Management System: Advanced
Technical and organisational conditions and measures:
Local exhaust ventilation: No
Effectiveness (%):
0
Route affected:
inhalation
Effectiveness (%):
0
Route affected:
dermal
Personal protection equipment:
Respiratory protection: No
Effectiveness (%):
0
Route affected:
inhalation
Personal protection equipment:
Dermal protection: Yes (Chemically resistant gloves conforming to EN374) and (other) appropriate dermal protection
Effectiveness (%):
80
Route affected:
dermal
Place of use:
indoor
Operating temperature (°C):
40
Type of exposure:
inhalation (external) long-term exposure
Exposure estimate:
2.083 mg/m³
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers
Version of exposure estimation tool:
3.0
Type of exposure:
inhalation (external) short-term exposure
Exposure estimate:
2.083 mg/m³
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers
Version of exposure estimation tool:
3.0
Type of exposure:
dermal (external) long-term exposure
Exposure estimate:
0.068 mg/kg bw/day
Exposure estimation method:
exposure estimation tool
Exposure estimation tool name:
ECETOC TRA workers
Version of exposure estimation tool:
3.0
Reason / purpose for cross-reference:
data waiving: supporting information
Reference

The water solubility of the test substance, was determined using the shake flask method according to OECD Guideline 105 and EU Method A.6 (Wohr, 2019).

Water solubility:
10.2 mg/L
at the temperature of:
20 °C

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion