Registration Dossier
Registration Dossier
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EC number: 294-347-7 | CAS number: 91697-85-7
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 09.04.2018 - 26.09.2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Version / remarks:
- 1992
- Deviations:
- no
- GLP compliance:
- no
- Remarks:
- ISO 9001 / ISO 14001 environment
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, non-adapted
- Details on inoculum:
- The study consisted of six bottles:
2 inoculum blanks (no test item),
2 test bottles (35730),
1 procedure control (sodium acetate) and
1 toxicity control (35730 plus sodium acetate). - Duration of test (contact time):
- >= 28 - <= 28 d
- Initial conc.:
- >= 15 - <= 15 mg/L
- Based on:
- ThCO2
- Remarks:
- 2.9 mg
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- The study procedures described in this report were in compliance with the OECD guideline
No. 301 B, 1992. In addition, the procedures were designed to meet the test methods of the
ISO standard 10634, 1995. - Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- >= 59 - <= 61
- Sampling time:
- 28 d
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Executive summary:
The relative biodegradation values calculated from the measurements performed during the test period revealed 61% and 59% biodegradation of 35730, for vessel A and B, respectively (based on ThCO 2 ). Therefore, average biodegradation of the test item after 28 days is 60%. Since the test item consists of a mixture of structurally similar chemicals, the 10-day window need not be applied.
In the toxicity control, more than 25% biodegradation occurred within 14 days (53%, based on ThCO 2 ). Therefore, the test item was assumed not to inhibit microbial activity.
Reference
Description of key information
The relative biodegradation values calculated from the measurements performed during the test period revealed 61% and 59% biodegradation of 35730, for vessel A and B, respectively (based on ThCO 2 ).
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
- Type of water:
- other: Milli-RO water
Additional information
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