Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 619-642-3 | CAS number: 106-78-5
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- not specified
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- CHLOROACETIC ACID CAS N°: 79-11-8
- Author:
- UNEP Publications
- Year:
- 1 994
- Bibliographic source:
- http://www.inchem.org/documents/sids/sids/79118.pdf
- Report date:
- 1994
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Cell Multiplication Inhibition Test, DIN 38412, part 9, 1988. End point: biomass determination.
- GLP compliance:
- no
Test material
- Reference substance name:
- Chloroacetic acid
- EC Number:
- 201-178-4
- EC Name:
- Chloroacetic acid
- Cas Number:
- 79-11-8
- Molecular formula:
- C2H3ClO2
- IUPAC Name:
- 2-Chloro-ethanoic acid
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Test solutions
- Vehicle:
- not specified
Test organisms
- Test organisms (species):
- Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)
Study design
- Test type:
- not specified
- Water media type:
- freshwater
Test conditions
- pH:
- 8.1 - 9.6
- Reference substance (positive control):
- not specified
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- EC10
- Effect conc.:
- 0.007 mg/L
- Basis for effect:
- biomass
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.028 mg/L
- Basis for effect:
- biomass
- Duration:
- 48 h
- Dose descriptor:
- EC10
- Effect conc.:
- 0.014 mg/L
- Basis for effect:
- growth rate
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.07 mg/L
- Basis for effect:
- growth rate
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- Algae were the most sensitive aquatic species. An EC10 48h growth rate of 0.014 mg/L and an EC50 48h growth rate of 0.07 mg/l were determined.
In the ECHA registration dossier for chloroacetic acid (CAS 79-11-8) an EC50 72h value for growth rate was determined, which lays in the range 0,01 < L(E)C50 < 0,1 and an NOEC 72h value for grwoth rate was determined which lays in the range 0,001 < NOEC < 0,01.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
