Condensation products of N-(6-aminohexyl)-12-hydroxyoctadecanamide and sebacic acid

Short-term toxicity to aquatic invertebrates

Link to relevant study record(s)

Reference

Endpoint:

short-term toxicity to aquatic invertebrates

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2018

Reliability:

1 (reliable without restriction)

Qualifier:

according to guideline

Guideline:

OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Analytical monitoring:

yes

Remarks:

It will be difficult due to the very low water soulbilty

Details on sampling:

0, 24 and 48 hours

Vehicle:

not specified

Test organisms (species):

Daphnia magna

Test type:

static

Water media type:

freshwater

Limit test:

yes

Total exposure duration:

48 h

Hardness:

140 and 250 mg/L as CaCO3

Test temperature:

20 ± 2 °C

pH:

6.0 to 9.0

Dissolved oxygen:

≥ 3 mg/L in control and test vessels

Salinity:

N/A

Nominal and measured concentrations:

currently less than the water solubility of < 0.00013 mg/L

Reference substance (positive control):

yes

Key result

Duration:

48 h

Dose descriptor:

LC50

Effect conc.:

ca. 0 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

other: limit of water solubility

Validity criteria fulfilled:

yes

Conclusions:

LD50 is < 0.00013 mg/L due to the limit of solubility, no effects observed.

Executive summary:

No effects observed at the limit of solubility

Description of key information

LD50 is < 0.00013 mg/L due to the limit of solubility, no effects observed. True value is below the value reported due to this being the limit of detection.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates

Effect concentration:

0 mg/L