N,N'-diphenylguanidine monohydrochloride

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

26 February 2018 to 21 March 2018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7200 (Melting Point / Melting Range)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

differential scanning calorimetry

Key result

Melting / freezing pt.:

>= 143.8 - <= 150.4 °C

Atm. press.:

1 013.25 hPa

Decomposition:

yes

Decomp. temp.:

>= 267 - <= 282 °C

Appearance of the Samples

Before the test the appearance of the test item was off-white powder. After the experiments the test item became a brown melt in the crucible.

 

Measurement

During the heating the test item showed endothermic signal in the temperature range of approx. 144 – 150 °C that can be associated with the melting of the test item.

In the temperature range between 267 – 282 °C one exothermic peak could be observed, which was assumed to the decomposition of the test item.

		Experiment 1	Experiment 2	Mean
Endotherm Peak	Onset of effect [°C]	144.19	143.48	143.84
	Endset of effect [°C]	150.41	150.32	150.37
	Energy [J/g]	-88.34	-87.52	-87.93
Exotherm Peak	Onset of effect [°C]	267.56	265.63	266.60
	Endset of effect [°C]	284.36	279.91	282.14
	Energy [J/g]	61.04	56.98	59.01

Conclusions:

The melting point was determined to be in range 143.8 to 150.4 °C followd by decomposition above 267 °C at 1013.25 hPa.

Executive summary:

A study was conducted according to OECD test guideline 102, Regulation (EC) No 440/2008 method A.1 and EPA OCSPP test guideline 830.7200 to determine the melting point of the test item using differential scanning calorimetry. The test item was weighed out into an aluminium crucible under an inert atmosphere (nitrogen). Two tests with about 3.90 mg of the test item were performed. As reference crucible, an empty aluminium crucible was used. The substance is a solid at ambient conditions. The prepared capsule was inserted into the furnace of the DSC device and heated from 25 °C to 500 °C with 10 °C /minutes heating rate. The melting point of the test item was determined to be in the range of 143.8 – 150.4 °C followed by decomposition in the range of 267 – 282 °C at 1013.25 hPa.

Description of key information

The substance melts in the range from 143.8 to 150.4 °C followed by decomposition in the range of 267 -282 °C.

Additional information

A study was conducted according to OECD test guideline 102, Regulation (EC) No 440/2008 method A.1 and EPA OCSPP test guideline 830.7200 to determine the melting point of the test item using differential scanning calorimetry. The test item was weighed out into an aluminium crucible under an inert atmosphere (nitrogen). Two tests with about 3.90 mg of the test item were performed. As reference crucible, an empty aluminium crucible was used. The substance is a solid at ambient conditions. The prepared capsule was inserted into the furnace of the DSC device and heated from 25 °C to 500 °C with 10 °C /minutes heating rate. The melting point of the test item was determined to be in the range of 143.8 – 150.4 °C followed by decomposition in the range of 267 – 282 °C at 1013.25 hPa.