Disodium 3,3'-[carbonylbis[imino(3-methoxy-4,1-phenylene)azo]]bis[benzenesulphonate]

Water solubility

Administrative data

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

Experimental starting date: 28 April 2017; Experimental completion date: 03 November 2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2018

Report date:

2018

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

flask method

Test material

Test material information

Constituent 1

Reference substance name:

Disodium 3,3'-[carbonylbis[imino(3-methoxy-4,1-phenylene)azo]]bis[benzenesulphonate]

EC Number:

233-316-4

EC Name:

Disodium 3,3'-[carbonylbis[imino(3-methoxy-4,1-phenylene)azo]]bis[benzenesulphonate]

Cas Number:

10114-86-0

Molecular formula:

C27H22N6Na2O9S2

IUPAC Name:

disodium 3,3'-[carbonylbis[imino(3-methoxy-4,1-phenylene)azo]]bis[benzenesulphonate]

Test material form:

solid: particulate/powder

Details on test material:

Identification: CIM-42(Direct Yellow 132)
Appearance/physical state: dark orange colored powder
Batch: 161011K
Purity: 94.0%
Expiry / Retest date: 01 December 2017
Storage conditions: Room temperature, in the dark over silica

Results and discussion

Water solubility

Key result

Water solubility:

132 g/L

Conc. based on:

test mat.

Temp.:

20 °C

pH:

>= 6.8 - <= 7

Any other information on results incl. tables

Preliminary Visual Evaluation of Solubility:

Observations recorded following re-equilibration at 20.0 °C are shown in the following table:

Nominal Loading Rate (% w/w)	Actual Loading Rate (% w/w)	Observations
15	12.4	A clear, dark orange colored solution containing significant excess, undissolved test item.
20	20.0	An orange colored paste, with no visible liquid present.
30	30.0	An orange colored paste/granular mass, with no visible liquid present.
40	39.9	A dark orange wetted powder, with no visible liquid present.
50	49.9	A dark orange wetted powder, with no visible liquid present.

Preliminary Analytical Test:

The preliminary estimate of the water solubility at 20.0 ± 0.5 °C was 138 g/L. 

Definitive Test:

The mean peak areas relating to the standard and sample solutions are shown in the following table:

Solution	Mean Peak Area
Standard solution, 255 mg/L	2.8733 x 10^7
Standard solution, 259 mg/L	2.7990 x 10^7
Matrix blank	none detected
Sample 1A	2.8695 x 10^7
Sample 1B	2.9353 x 10^7
Sample 2A	2.9128 x 10^7
Sample 2 B	2.9154 x 10^7
Sample 3A	2.9720 x 10^7
Sample 3B	2.9037 x 10^7

 

The concentration (g/L) of test item in the sample solutions is shown in the following table:

Sample Number	Time Shaken at  30 ºC (hours)	Concentration (g/L)	Solution pH
1	24	132	6.8
2	48	132	6.9
3	72	133	7.0

Mean concentration   :           132 g/L at 20.0 ± 0.5 ºC
Range                         :          132 to 133 g/L
Standarddeviation    :           0.821

Validation:

The linearity of the detector response with respect to concentration was assessed over the nominal concentration range of 100 to 400 mg/L. The results were satisfactory with afirst ordercorrelation coefficient (r) of 0.9997 being obtained.

Applicant's summary and conclusion

Conclusions:

The water solubility of the test item has been determined to be 132 g/L of solution at 20.0 ± 0.5 °C.

Executive summary:

The determination was carried out by a flask method, using a procedure designed to be compatible with Method A.6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.

The water solubility of the test item has been determined to be 132 g/L of solution at 20.0 ± 0.5 °C.