Registration Dossier
Registration Dossier
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EC number: 269-246-6 | CAS number: 68201-95-6
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.1 mg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 100 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.01 mg/L
- Assessment factor:
- 100 000
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 10 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.37 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.037 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.015 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Adequate chronic toxicity data are not available for Direct Red 253, therefore the aquatic toxicity assessment and classification are based mainly on the short-term toxicity data available on the substance and on analogue Similar Substance 01.
The key values chosen for Chemical Safety Assessment concerning the aquatic compartment are the following:
- for the short-term toxicity to fish the LC50 (96h) resulted to be greater than 1000 mg/l
- for short-term toxicity to aquatic invertebrates the EC50 (48h) resulted to be greater than 100 mg/l
- for toxicity to aquatic algae and cyanobacteria the EC50 (72 h) has been identified as higher than 100 mg/l
- for toxicity to microorganisms the no inhibition was recorded at dose of 100 mg/l
The substance resulted to be non harmful/toxic for none of the tested organisms, thus the limit value of 100 mg/l has been chosen for the PNEC freshwater water (both freshwater and marine water) derivation.
Conclusion on classification
Adequate chronic toxicity data are not available; Direct Red 253 is very water soluble, not readily biodegradable and has a negative log kow.
On the basis of the short-term toxicity data on the three trophic levels (details above), Direct Red 253 does not meet the criteria to be classified as hazard to the aquatic environment, according to the CLP Regulation (EC 1272/2008).
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