Registration Dossier
Registration Dossier
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EC number: 943-210-6 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
48 hour–EC50 = 39.1 mg/l (95% confidence limit: 29.0 – 48.7 mg·L-1)
48 hour–EC0 = 25.2 mg/l
48 hour–EC100 > 86.9 mg/l
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 39.1 mg/L
Additional information
The substance was tested in acute immobilisation test on Daphnia magna. The test was performed according to method C.2 – Daphnia sp. Acute Immobilisation Test, Council Regulation (EC) No. 440/2008, published in O.J.L 142, 2008.
The preliminary test was performed in a range of the test substance nominal concentrations 1 – 100 mg/l. Based on toxicity of the test substance found in the preliminary test, the definitive test was performed in appropriate concentration range.
It was observed that the test substance precipitated from the solution during the preliminary test. Because the test substance precipitated from the solution, the definitive test was performed under semi-static conditions.
The definitive semi-static test was performed in a range of the test substance nominal concentrations 33 – 125 mg/l. The test solutions were renewed after 24 hours. The test substance concentrations was measured at the beginning, after 24 hours (before and after renewal) and at the end of the test. The samples for analysis were taken from the clear solution above the precipitate in the definitive semi-static test.
There is stated in the guideline that, if evidence is available to demonstrate that the concentration of the test substance has been satisfactorily maintained within ± 20 percent of the nominal or measured initial concentration throughout the test, the results can be based on nominal or measured initial values.
Because concentrations of the test substance have not been satisfactorily maintained within ± 20 percent of the nominal or measured initial concentration throughout the test, time-weighted mean concentrations were used for all evaluations and results.
Test results:
48 hour–EC50 = 39.1 mg/l (95% confidence limit: 29.0 – 48.7 mg/l)
48 hour–EC0 = 25.2 mg/l
48 hour–EC100 > 86.9 mg/l
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