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EC number: 223-095-2 | CAS number: 3734-33-6
Endpoint summary
Administrative data
Description of key information
Adsorption/desorption:
The adsorption coefficient Koc in soil and in sewage sludge of Denatonium benzoate (powder) (CAS No. 3734-33-6)was determined by the Reverse Phase High Performance Liquid Chromatographic method according to OECD Guideline No. 121 for testing of Chemicals. The reference substances were chosen according to estimated Kocrange of the test substance and generalized calibration graph was prepared. The reference substances were 4 chloroaniline, 4 methylaniline, N methylaniline, 2 Nitrophenol, Nitrobenzene, 4-Nitrobenzamide, N,N-dimethylbenzamide, N-methylbenzamide, Benzamide, phenanthrene having Kocvalue ranging from 1.239 to 4.09. The Log Kocvalue was determined tobe 3.392± 0.007at 25°C. On the basis of log Koc value it is concluded that test chemical Denatonium benzoate has strong sorption to soil and sediment and therefore has negligible migration potential to ground water.
Additional information
Adsorption/desorption:
Different experimental data studies have been conducted for adsorption endpoint for test chemical Denatonium benzoate in different forms i.e., granular form and powder form and results of all the studies are summarized below.
First experimental study was done by UERL laboratory (2015) in this study the adsorption coefficient Koc in soil and in sewage sludge of Denatonium benzoate (powder) (CAS No. 3734-33-6)was determined by the Reverse Phase High Performance Liquid Chromatographic method according to OECD Guideline No. 121 for testing of Chemicals. The reference substances were chosen according to estimated Kocrange of the test substance and generalized calibration graph was prepared. The reference substances used were 4 chloroaniline, 4 methylaniline, N methylaniline, 2 Nitrophenol, Nitrobenzene, 4-Nitrobenzamide, N,N-dimethylbenzamide, N-methylbenzamide, Benzamide, phenanthrene having Koc value ranging from 1.239 to 4.09. The Log Kocvalue was determined to be 3.392± 0.007at 25°C. On the basis of log Koc value it is concluded that test chemical Denatonium benzoate has strong sorption to soil and sediment and therefore has negligible migration potential to ground water.
Another experimental study was also conducted by UERL lab (2015) in this study the adsorption coefficient Koc in soil and in sewage sludge of Denatonium benzoate (Granules) (CAS No. 3734-33-6) was determined by the Reverse Phase High Performance Liquid Chromatographic method according to OECD Guideline No. 121 for testing of Chemicals. The reference substances were chosen according to estimated Koc range of the test substance and generalized calibration graph was prepared. The reference substances were 4 chloroaniline, 4 methylaniline, N methylaniline, 2 Nitrophenol, Nitrobenzene, 4-Nitrobenzamide, N,N-dimethylbenzamide, N-methylbenzamide, Benzamide, phenanthrene having Kocvalue ranging from 1.239 to 4.09. The Log Koc value was determined to be 3.551± 0.071at 25°C. On the basis of log Koc value it is concluded that test chemical Denatonium benzoate has strong sorption to soil and sediment and therefore has negligible migration potential to ground water.
Last study was experimental study ( from European Draft Assessment Report, 2008) in this report the leaching behaviour of denatonium benzoate was assessed using the column leaching method in four different soil types. In three of the soils less than 0.05% of Denatonium benzoate (BITREX) appeared in the leachate. This indicates a strong adsorption of BITREX to those soils. However in the Boghall soil about 10% AR appeared in the leachate.It should be noted that due to the high amount of organic matter present in theBoghallsoil and its repellent properties to water the soil column was incompletely watering.In conclusion, denatonium benzoate has a high affinity to soil and has negligible potential for leaching.
On the basis of results of all above mentioned studies it is concluded that the test chemical Denatonium benzoate (CAS 3734 -33 -6) has a strong sorption to soil and sediment and therefore has negligible migration potential to groundwater.
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