Registration Dossier
Registration Dossier
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EC number: 701-005-7 | CAS number: -
Bioaccumulation: aquatic / sediment
Administrative data
- Endpoint:
- bioaccumulation in aquatic species: fish
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: peer reviewed publication
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Higher alcohols bioconcentration: Influence of biotransformation
- Author:
- De Wolf W, Parkerton TF
- Year:
- 1 999
- Bibliographic source:
- Extended Abstracts of the 217th ACS National Meeting, Anaheim, CA, Symposium "Persistent, Bioaccumulative, Toxic Chemicals, March 21-25, 1999
- Report date:
- 1999
- Reference Type:
- secondary source
- Title:
- SIDS Initial Assessment Report for SIAM 22
- Author:
- OECD SIAM 22
- Year:
- 2 006
- Report date:
- 2006
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 305 (Bioconcentration: Flow-through Fish Test)
- GLP compliance:
- no
Test material
- Details on test material:
- Branched commercial alcohols with chain-lengths of C10, C12 and C13 carbons
Constituent 1
Test organisms
- Test organisms (species):
- Oncorhynchus mykiss (previous name: Salmo gairdneri)
- Details on test organisms:
- TEST ORGANISM
- Common name: rainbow trout
- Age at study initiation: juvenile
- Weight at study initiation: 0.2 - 0.9 g
- Lipid content: 3.5 - 5.8%
Study design
- Route of exposure:
- aqueous
- Test type:
- flow-through
- Water / sediment media type:
- natural water: freshwater
- Total exposure / uptake duration:
- 10 d
- Total depuration duration:
- 4 d
Results and discussion
Bioaccumulation factor
- Type:
- BCF
- Value:
- < 100
- Details on results:
- - Uptake phase: fish attained rapidly a steady-state concentration of alcohols
- Rapid elimination occurred after transfer to clean water
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
