2-Propanol, 1-amino-, compds. with polyethylene glycol hydrogen sulfate C12-14-alkyl ethers

Partition coefficient

Link to relevant study record(s)

Reference

Endpoint:

partition coefficient

Type of information:

experimental study

Adequacy of study:

key study

Study period:

5-9 Dec 2011

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 123 (Partition Coefficient (1-Octanol / Water), Slow-Stirring Method)

Deviations:

yes

Remarks:

end detection by ISO 2271 for the anionic surfactant

Principles of method if other than guideline:

Literature: D. Miller; Tenside, Surf. Det. 47 (2010), 28-33: Octanol-Water Partition Coefficients of Surfactants: Slow Stirring / Surface Tension Method.

GLP compliance:

no

Type of method:

slow-stirring method

Partition coefficient type:

octanol-water

Analytical method:

other: titration

Type:

log Pow

Partition coefficient:

1

Temp.:

23 °C

pH:

>= 6 - <= 7

Results of 3 determinations:

Quantity, unit	Determination 1	Determination 2	Determination 3
Temperature, °C	23	23	23
Stirring velocity, r/min	100	100	100
Volume of Erlenm. flask, mL	250	250	250
Amount of test subst., mg	345	105	201
Concentration of active matter in test subst., g/100 g	94.4	94.4	94.4
Volume of water, mL	200	100	50
pH value of water layer	7.2	7.4	6.8
Volume of octanol, mL	20	20	100
Duration of stirring, hrs	24	24	24
Molecular weight of test subst., g/mol	439	439	439
Concentration of titrant (Hyamine), mol/L	0.004	0.004	0.004
Factor of titrant (Hyamine)	0.979	0.979	0.979
Used volume of octanol layer for titration, mL	1	1	5
Consumption of titration of octanol layer, mL	3.98	1.84	4.46
Amount of test subst. in octanol layer, mg	136.84	63.26	153.35
Concentration of test subst. in octanol layer, g/L	6.84	3.16	1.53
Used volume of aqueous layer for titration, mL	10	20	10
Consumption of titration of aqueous layer, mL	4.64	3.50	1.07
Amount of test subst. in aqueous layer, mg	159.53	30.08	9.20
Concentration of test subst. in aqueous layer, g/L	0.80	0.30	0.18
Total amount of test subst. recovered, mg	296.38	93.35	162.54
Recovery rate, %	91	94	86
Measured concentration in octanol layer, mmol/L	15.59	7.21	3.49
Measured concentration in aqueous layer, mmol/L	1.82	0.69	0.42
Log Pow	0.9	1.0	0.9
Log Pow mean value	1.0

Description of key information

log Pow = 1.0 at 23 °C, pH 6-7

Key value for chemical safety assessment

Log Kow (Log Pow):

1

at the temperature of:

23 °C

Additional information

The partition coefficient of the substance was determined using slow stirring method according to OECD 123.