Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

Currently viewing:

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Peer reviewed data

Data source

Reference
Reference Type:
review article or handbook
Title:
Documentation of the Threshold Limit Values and Biological Exposure Indices.
Author:
American Conference of Governmental Industrial Hygienists, Inc.
Year:
1991
Bibliographic source:
6th ed. Volumes I, II, III. Cincinnati, OH: ACGIH

Materials and methods

Principles of method if other than guideline:
No data

Test material

Constituent 1
Chemical structure
Reference substance name:
Chloroacetyl chloride
EC Number:
201-171-6
EC Name:
Chloroacetyl chloride
Cas Number:
79-04-9
Molecular formula:
C2H2Cl2O
IUPAC Name:
2-chloroacetyl chloride

Test animals

Species:
rat

Administration / exposure

Route of administration:
oral: unspecified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
208 mg/kg bw

Applicant's summary and conclusion

Interpretation of results:
Toxicity Category III
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
LD50 Rat oral 208 mg/kg
Executive summary:

LD50 Rat oral 208 mg/kg