Registration Dossier
Registration Dossier
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EC number: 220-667-3 | CAS number: 2855-19-8
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
A new guideline study (OECD 209) according to GLP is available for decyloxirane. After 3h exposure the EC10 and EC50 were
determined to be 36 mg/l and > 1000 mg/l, respectively.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 1 000 mg/L
- EC10 or NOEC for microorganisms:
- 36 mg/L
Additional information
A new guideline study (OECD 209) according to GLP is available for decyloxirane. After 3h exposure the EC10 and EC50 were determined to be 36 mg/l and > 1000 mg/l, respectively.
Further tests with microorganisms are available, however, they were not used for the derivation of the PNEC microorganisms since they were performed with the microorganism Vibrio fisheri. Fibrio fisheri , however, is according to Tab. R10-6 Test sustems for derivation of PNEC microorganisms a marine species , with only a limited relevance for STP functioning. Therefore , the inhinbition control of the OECD 301 B test was used to deviate the PNEC microorganisms.
Test with fibrio fischeri:
The test item was investigated for toxicity to bacteria. In a scientifically well-documented, non-standard, non-GLP study, bacteria of the strain Vibrio fischeri were exposed to the test item in two to four replicates at different concentrations. In a 24 h-growth inhibition test, an EC50 of 47.9 mg/L test item was estimated.
In the same study, the test item was investigated for short-term toxicity in a 30 min-bioluminescence inhibition test with the bacterium Vibrio fischeri. .In this test, an EC50 value of 1.2 mg/L was estimated. (Blaschke et al, 2010)
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