Registration Dossier
Registration Dossier
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EC number: 220-612-3 | CAS number: 2835-68-9
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2009
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: testing method performed according to OECD107
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 009
- Report date:
- 2009
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- GLP compliance:
- not specified
- Type of method:
- shake-flask method to: flask method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- p-aminobenzamide
- EC Number:
- 220-612-3
- EC Name:
- p-aminobenzamide
- Cas Number:
- 2835-68-9
- Molecular formula:
- C7H8N2O
- IUPAC Name:
- 4-aminobenzamide
Constituent 1
Study design
- Analytical method:
- photometric method
Results and discussion
Partition coefficient
- Type:
- log Pow
- Partition coefficient:
- -0.38
- Temp.:
- 23 °C
- pH:
- ca. 7
Any other information on results incl. tables
Table 1: Results in detail
determ. no. |
stock solution [ml] | water [ml] | test substance conc. in n-octanol phase [mg/l] | test substance conc. in water phase [mg/l] | log Pow |
| A1 | 5 | 10 | 372,1 | 153,6 | -0,38 |
| A2 | 5 | 10 | 369,3 | 153,1 | -0,38 |
| B1 | 10 | 10 | 474,2 | 195,9 | -0,38 |
| B2 | 10 | 10 | 470,0 | 196,3 | -0,38 |
| C1 | 20 | 10 | 552,2 | 230,4 | -0,38 |
| C2 | 20 | 10 | 553,7 | 228,6 | -0,38 |
| mean | --- | --- | --- | --- | -0,38 |
Stock solution: 667,0 mg/I
Applicant's summary and conclusion
- Conclusions:
- Due to the partition coefficient n-octanol-water bioaccumulation is not expected.
- Executive summary:
The Log Pow of the test item was determined with the shake-flask method according to OECD 107. It was found to be -0.38 at 23°C.
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