Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Study not well documented. Only results available.

Data source

Reference
Reference Type:
publication
Title:
No information
Year:
1953
Bibliographic source:
NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC), Volume(issue)/page/year: 5,46,1953

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
no information
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
1-amidino-2-thiourea
EC Number:
218-308-0
EC Name:
1-amidino-2-thiourea
Cas Number:
2114-02-5
Molecular formula:
C2H6N4S
IUPAC Name:
1-(Diaminomethylidene)thiourea
Test material form:
solid: crystalline

Test animals

Species:
rat

Administration / exposure

Route of administration:
oral: unspecified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
> 500 mg/kg bw
Based on:
test mat.

Applicant's summary and conclusion

Interpretation of results:
Category 4 based on GHS criteria