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EC number: 275-639-3 | CAS number: 71566-54-6
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Not readily biodegradable (according to OECD criteria).
Key value for chemical safety assessment
Additional information
Data on the ready biodegradability of the described 'red disazo pigment' are not available. However, two model calculations were conducted to assess the biodegradability in a weight of evidence. The EPI Suite v4.11 (BIOWIN Program v4.10) calculation resulted in "not readily biodegradable". Additionally, the biodegradation was calculated by using CATALOGIC v5.13.1 (BOD 28 days MITI (OECD 301C) v11.15). It resulted in ca. 3 % biodegradation after 28 d.
Moreover, the 'red disazo pigment' is practically insoluble and therefore considered to be essentially not bioavailable. Due to the large molecular size, cellular uptake of the pigment is unlikely. Hence intracellular biodegradation, which is the main degradation route of bacteria, is probably low. It can be concluded that the substance is likely to persist in the environment.
The dispersion stability of Pigment Red 221 was strongly depended on water hardness. Dissolution was excluded as the main cause of the apparent stability. In very hard water with 10 mM Ca(NO3)2 and/or pH 4, the dispersion stability of the tested substance was low. At all other conditions, the dispersion stability was at least intermediate. At pH 9 with 0 or 1 mM Ca(NO3)2, the stability was high.
Nanomaterials do not reach a thermodynamical equilibrium between dispersed and dissolved phase. Nevertheless, the amount of the dissolved part is negligible due to the low solubility. The majority of the compound will be in its dispersed form which is still accessible for microorganisms.
For this reason no ready or inherent degradation studies are proposed.
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